نتایج جستجو برای: solid cancer
تعداد نتایج: 1083074 فیلتر نتایج به سال:
Background: We investigated whether a three-dimensional (3D) analysis could correct the discrepancy between conventional computed tomography findings and pathological contribute to prognostic stratification in early pure solid lung cancer.
Deregulated ribosomal RNA synthesis is associated with uncontrolled cancer cell proliferation. RNA polymerase (Pol) I, the multiprotein complex that synthesizes rRNA, is activated widely in cancer. Thus, selective inhibitors of Pol I may offer a general therapeutic strategy to block cancer cell proliferation. Coupling medicinal chemistry efforts to tandem cell- and molecular-based screening led...
BACKGROUND Only limited data on the prevalence of iron deficiency (ID) and its correlation with clinical parameters are available in cancer. ID frequently contributes to the pathogenesis of anemia in patients with cancer and may lead to several symptoms such as impaired physical function, weakness and fatigue. PATIENTS AND METHODS Parameters of iron status and clinical parameters were evaluat...
High-intensity focused ultrasound (HIFU) is a novel therapeutic modality that permits noninvasive treatment of various benign and malignant solid tumors, including prostatic cancer, uterine fibroids, hepatic tumors, renal tumors, breast cancers, and pancreatic cancers. Several preclinical and clinical studies have investigated the safety and efficacy of HIFU for treating solid tumors, including...
Inside Back Cover In article number 2200570, Ma, Xu, and co-workers highlight the biophysical cue, a new hallmark of cancer, serving as significant factor in tumor microenvironment forming physical microenvironment, including extracellular matrix microarchitecture, stiffness, interstitial fluid pressure, solid stress. It plays an essential role affecting radiotherapy efficacy. Meanwhile, also a...
Sex hormone-binding globulin (SHBG) is the major carrier protein of testosterone and estradiol in the blood. Although studies on the role of SHBG in ovarian cancer are inconclusive, substantial evidence indicates that SHBGsteroid complexes can play a direct role in the intracellular transport of steroids to cancer cells. SHBG is synthesized in the adult liver of many species, excluding rodents....
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