Unprotected exposure of skin to solar ultraviolet radiation (UVR) may damage the DNA cells and can lead cancer. Sunscreens are topical formulations used protect against UVR. The active ingredients sunscreens UV filters that absorb, scatter, and/or reflect Preventing formation free radicals repairing damages, natural antioxidants also added as a second fold protection Antioxidants help stabilise...

—The roles of temperature and ultraviolet radiation (UVR) in determining the spawning success of yellow perch Perca flavescens were investigated in two Pennsylvania lakes with different dissolved organic carbon (DOC) concentrations. In situ incubation experiments were used to manipulate temperature and UVR and to examine hatching time and hatching success. Extensive scuba surveys were used to d...

One of the physiologic consequences of excessive UV radiation (UVR) exposure is apoptosis. This critical response serves to eliminate genetically injured cells and arises, in part, from activation of DNA damage and p53 signaling. Other contributory pathways, however, likely exist but have not been fully characterized. In a recent global screen of UVR response genes in melanocytes, we identified...

During leisure time, people can decide if they want to expose themselves solar ultraviolet (UV) radiation and what extent. While working, do not have this choice. Outdoor workers are exposed UV (UVR) on a daily basis. This may pose certain health risk, which be estimated when the personal UVR exposure (PE) is known. past decades, variety of studies were conducted measure PE outdoor our knowledg...

We present here that Heat shock protein 90 (Hsp90) inhibitor 17-(allylamino)-17demethoxygeldanamycin (17AAG), when topically applied to mouse skin, inhibits ultraviolet radiation (UVR)-induced development of cutaneous squamous cell carcinoma (SCC). In these experiments, DMSO:acetone (1:40 v/v) solution of 17AAG (500nmol) was applied topically to mouse skin in conjunction with each UVR exposure ...

Chronic exposure of the opossum Monodelphis domestica to UV radiation (UVR) leads to the formation of cutaneous and corneal tumors. Groups of shaved opossums were exposed 3 times/week to: (a) UVR alone; (h) UVR followed immediately by l h of photoreactivating light (PRL) (320-700 nm); (c) l h of PRL followed by UVR; and (rf) l h of PRL alone. Exposures were terminated after 70 weeks of treatmen...

Chronic exposure of the opossum Monodelphis domestica to UV radiation (UVR) leads to the formation of cutaneous and corneal tumors. Groups of shaved opossums were exposed 3 times/week to: (a) UVR alone; (b) UVR followed immediately by 1 h of photoreactivating light (PRL) (320-700 nm); (c) 1 h of PRL followed by UVR; and (d) 1 h of PRL alone. Exposures were terminated after 70 weeks of treatment...

OBJECTIVE Solar ultraviolet radiation (UVR) exposure is widely recognised as a leading cause of skin cancer, with outdoor workers being particularly at risk. Little is known on a national level about how many workers are exposed to solar radiation, the circumstances in which they are exposed, or their use of protective measures. METHODS The Australian Work Exposures Study (AWES) was a cross-s...

Green tea catechins (GTC) reduce UV radiation (UVR)-induced inflammation in experimental models, but human studies are scarce and their cutaneous bioavailability and mechanism of photoprotection are unknown. We aimed to examine oral GTC cutaneous uptake, ability to protect human skin against erythema induced by a UVR dose range and impact on potent cyclo-oxygenase- and lipoxygenase-produced med...