Based on our experience in hemodiafiltration unit we would recommend a personalized isonatremic dialysate bath. We currently prescribe 137 meq (isonatremic) or delta Na/serum Na less than 2 meq. In addition to the sodium prescribed dialysate, for majority of patients do not restrict dietary water intake. The average intake is 2775 mg per day and blood pressure maintained without hypertensive me...

We have been systematically testing the idea that the intracellular concentration of sodium is higher in transformed cells than in their normal counterparts and the idea that the sodium concentration is also higher in rapidly dividing cell populations than in slowly dividing cell populations. Unfixed freeze-dried and uncoated tissue sections of 18 normal and 4 tumor cell populations were subjec...

Perfusion and sodium secretion parameters were measured in the isolated rectal gland of Scyliorhinus canicula L. perfused at in vivo pressures, and the effect of stimulation of secretory activity by cyclic AMP and theophylline on these parameters was determined. Stimulation resulted in large increases in secretion flow rate, percentage extraction of sodium from the perfusing fluid, and arteriov...

Fang, Zhiwu, Scott H. Carlson, Ning Peng, and J. Michael Wyss. Circadian rhythm of plasma sodium is disrupted in spontaneously hypertensive rats fed a high-NaCl diet. Am J Physiol Regulatory Integrative Comp Physiol 278: R1490–R1495, 2000.—High-NaCl diets elevate arterial pressure in NaCl-sensitive individuals, and increases in plasma sodium may trigger this effect. The present study tests the ...