introduction: brachytherapy is the use of small encapsulated radioactive sources in close vicinity of tumors. various methods are used to obtain the dose distribution around brachytherapy sources. tg-43 is a dosimetry protocol proposed by the aapm for determining dose distributions around brachytherapy sources. the goal of this study is to update this protocol for presence of bone and air inhom...

introduction: mesenchymal stem cells (mscs) hold great promise in the field of regenerative medicine.although originally isolated from bone marrow, mscs have since been obtained from a variety of adult and neonatal tissues including the adipose tissue. stemness and multipotential features of mesenchymal stem cells (msc) has been highlighted in many studies but there are many dark aspects in exc...

One of the most common problems in Regenerative Medicine is the regeneration of damaged bone with the aim of repairing or replacing lost or damaged bone tissue by stimulating the natural regenerative process. Particularly in the fields of orthopedic, plastic, reconstructive, maxillofacial and craniofacial surgery there is need for successful methods to restore bone. From a regenerative point of...

Low dose microcomputed tomography (μCT) is a recently matured technique that enables the study of longitudinal bone healing and the testing of experimental treatments for bone repair. This imaging technique has been used for studying craniofacial repair in mice but not in an orthopedic context. This is mainly due to the size of the defects (approximately 1.0 mm) in long bone, which heal rapidly...

intraosseous ganglia can affect the carpal bones of the hand and must be considered in the differential diagnosis of wrist pain. a 38-year-old female presented with a 14-month history of left wrist pain and a radiolucent cystic lesion was seen computed tomography (ct) scanning. characteristic radiographic findings of a cyst in association with a fine sclerotic rim was apparent. we report an unu...

This is the first study to demonstrate that benzo(a)-pyrene (BaP) was able to enhance the production of parathyroid hormone‑related protein (PTHrP) by human non‑small cell lung cancer H460 cells. Such effect would further contribute to bone metastasis of lung cancer by increasing osteoclastogenesis. This study is also the first to reveal that tricetin (TCN), a flavonoid derivative found in Myrt...

Pretreatment lymph nodes. bone marrow. center cell (FCC) lymphomas (55%). The and blood were examined in 1 76 cases of pattern of bone marrow involvement was non-Hodgkins lymphoma. By the criteria of most frequently focal paratrabecular in Bthe Lukes and Collins functional-morphocell lymphomas and diffuse in T-cell logical classification. 1 58 (90%) were B-cell lymphomas. Blood involvement was ...

Imatinib mesylate is an effective, small-molecule, selective tyrosine kinase inhibitor, which inhibits BCR-ABL in patients with chronic myeloid leukemia, c-kit gastrointestinal tumor (GIST), and platelet-derived growth factors hypereosinophilic syndrome. Above all, bone marrow necrosis a rare complication of imatinib usage. If newly developed increased opacity lesions are seen metastatic GIST, ...

This paper presents the second and third stages of a multivariate taphonomic analysis of the bovid bone assemblage from Dunefield Midden (DFM), a Later Stone Age site on South Africa’s west coast. The second stage investigates bovid skeletal element abundance and longbone fragmentation patterns at the site. The third stage integrates these data with bone modification data (Stewart 2010) to expl...