Propagation of signals from the T cell antigen receptor (TCR) involves a number of adaptor molecules. SH2 domain-containing protein 76 (SLP-76) interacts with the guanine nucleotide exchange factor Vav to activate the nuclear factor of activated cells (NF-AT), and its expression is required for normal T cell development. We report the cloning and characterization of a novel Grb2-like adaptor mo...

PURPOSE: To compare the abilities of scanning laser polarimetry (SLP), optical coherence tomography (OCT), short-wavelength automated perimetry (SWAP), and frequency-doubling technology (FDT) perimetry to discriminate between healthy eyes and those with early glaucoma, classified based on standard automated perimetry (SAP) and optic disc appearance. To determine the agreement among instruments ...

We show how the event-based notation offered by Event-B may be augmented by algorithmic modelling constructs without disrupting the refinement-based development process.

PURPOSE To undertake a community (nonclinical) study to describe the speech of preschool children who had been identified by parents/teachers as having difficulties "talking and making speech sounds" and compare the speech characteristics of those who had and had not accessed the services of a speech-language pathologist (SLP). METHOD Stage 1: Parent/teacher concern regarding the speech skill...

To enhance the curcumin absorption by oral administration, liposome-encapsulated curcumin (LEC) was prepared from commercially available lecithins (SLP-WHITE and SLP-PC70) and examined for its interfacial and biochemical properties. A LEC prepared from 5 wt % of SLP-PC70 and 2.5 wt % of curcumin gave a good dispersibility with 68.0% encapsulation efficiency for curcumin, while those from SLP-WH...

‎In this paper‎, ‎we find matrix representation of a class of sixth order Sturm-Liouville problem (SLP) with separated‎, ‎self-adjoint boundary conditions and we show that such SLP have finite spectrum‎. ‎Also for a given matrix eigenvalue problem $HX=lambda VX$‎, ‎where $H$ is a block tridiagonal matrix and $V$ is a block diagonal matrix‎, ‎we find a sixth order boundary value problem of Atkin...

OBJECTIVE To identify the relationship between vocal self-assessment, the assessment of voice by a speech-language pathologist (SLP), and the effect of voice on the quality of life of patients with benign thyroid diseases. STUDY DESIGN Cross-sectional study. SETTING University hospital. SUBJECTS AND METHOD A total of 67 women with a mean age of 44.7 ± 14.8 years and a diagnosis of benign ...

In the Drosophila segmentation hierarchy, periodic expression of pair-rule genes translates gradients of regional information from maternal and gap genes into the segmental expression of segment polarity genes. In Tribolium, homologs of almost all the eight canonical Drosophila pair-rule genes are expressed in pair-rule domains, but only five have pair-rule functions. even-skipped, runt and odd...

In order to evaluate to the feasibility of using lecithins for nanocapsules including functional food materials, liposomes were prepared from different commercially available lecithins (SLP-WHITE, SLP-PC70 and PL30S) by the Bangham method, and their physicochemical properties were examined by using a confocal laser scanning microscopy (CLSM) and the measurements of trapping efficiency. There wa...

In contrast to the segmentation of the embryonic trunk region which has been extensively studied, relatively little is known about the development and segmentation of the Drosophila head. Proper development of the cephalic region requires the informational input of three of the four maternal coordinate systems. Head-specific gene expression is set up in response to a complex interaction between...