نتایج جستجو برای: skin stem cells

تعداد نتایج: 1665664  

Journal: :Global Pharmaceutical Research 2019

Ali Moravej, Bita Geramizadeh, Mahdokht Hossein Aghdaie Mohammad-Hossein Karimi Omid Kohi-Hoseinabadi Salimeh Ebrahimnezhad,

Background: Mesenchymal stem cells (MSCs) are considered as effective therapeutic cells in transplantation due to their immunomodulatory activities. However, precise mechanism of MSCs immunomodulatory activity is not completely understood. Objectives: To study the role of Immunoglobulin-like transcripts-3 (ILT3) immunomodulatory receptor in immune tolerance induced by MSCs in skin transpla...

Journal: :Stem cells 2011
Shanmugasundaram Natesan Nicole L Wrice David G Baer Robert J Christy

Major traumatic injuries to the body, such as large surface area burns, limit the availability of autologous stem cell populations for wound repair. This report demonstrates that even after severe burn trauma to the body, resident stem cells present within the subcutaneous adipose tissue survive and are available for therapeutic uses. Debrided skin from wounded areas contains subcutaneous adipo...

Journal: :Journal of Investigative Dermatology 1993

Journal: :Nature Reviews Molecular Cell Biology 2020

2016
Yoriko Sugiyama-Nakagiri Tsutomu Fujimura Shigeru Moriwaki

The generation of full thickness human skin from dissociated cells is an attractive approach not only for treating skin diseases, but also for treating many systemic disorders. However, it is currently not possible to obtain an unlimited number of skin dermal cells. The goal of this study was to develop a procedure to produce skin dermal stem cells from induced pluripotent stem cells (iPSCs). S...

Journal: :Skin pharmacology and physiology 2009
A Charruyer R Ghadially

Advances in tissue engineering of skin are needed for clinical applications (as in wound healing and gene therapy) for cutaneous and systemic diseases. In this paper we review the use of epidermal stem cells as a source of cells to improve tissue-engineered skin. We discuss the importance and limitations of epidermal stem cell isolation using biomarkers, in quest of a pure stem cell preparation...

Journal: :Journal of cell science 1996
M Michel N Török M J Godbout M Lussier P Gaudreau A Royal L Germain

This study was undertaken to evaluate keratin 19 (K19) as a biochemical marker for skin stem cells in order to address some long standing questions concerning these cells in the field of cutaneous biology. We first used the well-established mouse model enabling us to identify skin stem cells as [3H]thymidine-label-retaining cells. A site directed antibody was raised against a synthetic peptide ...

ژورنال: مجله طب نظامی 2022

War's nature is constantly changing over time with the progress in military technology and weapons of war, which has led to a diverse pattern of tissue injuries. Developments in personal protective equipment and body armor, rapid transfer from the battlefield to medical centers, improved resuscitation measures, bleeding control, and wound management have increasingly contributed to the wounded ...

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