asthma, who attended for the first time to Allergy Department and collected data on clinical history, respiratory function and allergic sensitization. Asthma severity was classified using the GINA guide. We integreted the data into regression models to identify allergen sensitization most strongly associated with asthma severity. Results: We included 260 children with ages ranging from 3 to 18 ...

asthma, who attended for the first time to Allergy Department and collected data on clinical history, respiratory function and allergic sensitization. Asthma severity was classified using the GINA guide. We integreted the data into regression models to identify allergen sensitization most strongly associated with asthma severity. Results: We included 260 children with ages ranging from 3 to 18 ...

OBJECTIVE Allergic rhinitis can determine the presence and type of asthma. The main aim of this study was to evaluate the link between allergic rhinitis, asthma, and skin test sensitization in patients with allergic rhinitis. METHODS Patients with allergic rhinitis, aged 10 to 50 years, were consecutively enrolled at different allergy centers in Spain and Portugal. All the patients underwent ...

Migraine headache is commonly associated with signs of exaggerated intracranial and extracranial mechanical sensitivities. Patients exhibiting signs of intracranial hypersensitivity testify that their headache throbs and that mundane physical activities that increase intracranial pressure (such as bending over or coughing) intensify the pain. Patients exhibiting signs of extracranial hypersensi...

A literature study was performed to evaluate dose-response relationships and no-effect levels for sensitization and elicitation in skin- and respiratory allergy. With respect to the skin, dose-response relationships and no-effect levels were found for both intradermal and topical induction, as well as for intradermal and topical elicitation of allergenic responses in epidemiological, clinical, ...

BACKGROUND Kathon CG is a commonly used cosmetic-grade preservative that contains active ingredients methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI). OBJECTIVE The aim of the study was to perform a skin sensitization induction risk assessment of daily exposure to Kathon CG after use of various personal care and cosmetic products. METHODS We calculated an estimated daily con...

BACKGROUND Chlorhexidine is used for disinfection of skin and mucosae in medicine and dentistry. Prolonged exposure may lead to contact sensitization and allergic contact dermatitis or stomatitis. OBJECTIVES The purpose of this study was to analyse the sources of chlorhexidine exposure and sensitization, and to obtain data on the prevalence of sensitization and chlorhexidine-related contact a...

Atopic dermatitis (AD) is a common allergic inflammatory skin disease caused by a combination of intense pruritus, scratching, and epicutaneous (e.c.) sensitization with allergens. To explore the roles of IL-21 and IL-21 receptor (IL-21R) in AD, we examined skin lesions from patients with AD and used a mouse model of allergic skin inflammation. IL-21 and IL-21R expression was upregulated in acu...

Background. Date palm's pollen has been identified as a source of allergy; the rate of sensitization of this pollen is between 6 and 29%. Objective. To determine the prevalence of sensitization to date palm in Marrakesh and to identify the clinical profile. Patients and Methods. This study is based on a questionnaire and the prick test on 7 allergens, in population aged 5 years and above with c...

asthma, who attended for the first time to Allergy Department and collected data on clinical history, respiratory function and allergic sensitization. Asthma severity was classified using the GINA guide. We integreted the data into regression models to identify allergen sensitization most strongly associated with asthma severity. Results: We included 260 children with ages ranging from 3 to 18 ...