Naevus lipomatosis cutaneous superficialis (NLCS) is a rare benign hamartoma of adipose tissue of the skin characterized by the presence of clusters of mature ectopic fat cells among the collagen bundles of the dermis. Usually, the number of adnexal structures is reduced in NLCS with preserved morphology. NLCS is also recognized as "Naevus lipomatosis of Hoffman and Zurhelle". NLCS is presented...

Multiple unresectable melanoma skin metastases pose a treatment problem, especially in centers where isolated limb perfusion is not available. We report the case of a 59-year-old woman who developed multiple small unresectable cutaneous melanoma metastases on the thigh after her lower limb was amputated. Electrochemotherapy with bleomycin resulted in good local control of the disease, with a co...

This report describes a rare form of scleroderma associated with multiple, elevated, dermal nodules. In addition, rare acid-fast bacteria, and less rare non-acid-fast coccoid forms were seen in histologic sections from the nodules. Skin culture isolates in thioglycolate broth were positive for both intermittently acid-fast coccobacilli, as well as non-acid-fast cocci compatible with Staphylococ...

Pancreatic panniculitis is a rare skin disorder that occurs in 2-3% of pancreatic diseases, mostly associated with acute or chronic pancreatitis. Its pathophysiology is still unclear, but the release of pancreatic enzymes in circulation can be responsible for this disorder. The typical histological features are adipocyte necrosis with neutrophils infiltrate and typical "ghost cells". Its treatm...

Phaeohyphomycosis (PHM) is a rare, deep fungal infection of the skin and subcutaneous tissues caused by dematiaceous fungi. In this report, we describe a case of PHM caused by Phaeoacremonium rubrigenum, which is generally known to infect woody plants. We detected the gray-blackish villi by biopsy culture material, and slide culture revealed the conidia arising from slightly tapering phialides....

Basal cell carcinoma is a malignant epithelial neoplasm of the skin and most common human cancer. It generally associated with good prognosis. In this case report, giant basal nodulo-ulcerative type showing wide ulceration marginal multiple small nodules, presented. was trapezoidal in shape, having dimensions 7 cm at greatest width, 6 vertically different anterior posterior margin dimensions, 5...

An 81-year-old Japanese man presented with dark blue papules and nodules on his face. There were multiple soft papules and nodules, dark blue in color, compressive, and ranging in size from 2 to 10 mm. A few similar lesions were seen on the patient's right dorsal second toe and right buccal mucosa. There were no skin lesions on his trunk and upper limbs. The patient's past history did not inclu...

zosteriform metastasis is a rare clinical distribution from spreading neoplasms of every organ to the skin. tumors most often arise from a n internal o r hematologic malignancy. w e report a 69-year-old man, a known case of malignant melanoma of the left heel. in this case, multiple red-brown metastatic nodules appeared four months after diagnosis. distribution of metastatic lesions resembled a...

Background: Metronidazole is categorized in pharmacological group C and few researches have been conducted about its pathological effects on the human fetus. Since the embryogenesis in chicken is similar to that in human beings, in the current study, the toxic effects of this drug on embryo skin and integument tissues were assessed using a chicken embryo model. Method:...

Granuloma faciale (GF) is a rare cutaneous disorder categorized as a localized form of small-vessel vasculitis. Clinically, it manifests as single or multiple well-demarcated red-brown plaques, papules and nodules, nearly always confined to the face. Herein, we report a 39-year-old man with multiple red-brown infiltrated plaques on face and extrafacial lesions on back, shoulders and both arms. ...