Lactate production in skeletal muscle has now been studied for nearly two centuries and still its production and functional role at rest and during muscle contraction is a subject of debate. Historically, skeletal muscle was seen mainly as the site of lactate production during contraction and lactate production associated with a lack of muscle oxygenation and fatigue. Later, it was recognized t...

objective: micrornas (mirnas) are a class of small non-coding rnas that play pivotal roles in many biological processes such as regulating skeletal muscle development where alterations in mirna expression are reported during myogenesis. in this study, we aimed to investigate the impact of predicted mirnas and their target genes on the myoblast to myocyte differentiation process. materials and m...

ABSTRACT First Person is a series of interviews with the first authors selection papers published in Journal Cell Science, helping early-career researchers promote themselves alongside their papers. Keira L. Rice author on ‘ Localized TPC1-mediated Ca2+ release from endolysosomes contributes to myoseptal junction development zebrafish’, JCS. PhD candidate lab Prof. Andrew Miller at Division Lif...