AIMS Heart rate reduction is the cornerstone of the treatment of angina. The purpose of this study was to explore the prognostic value of heart rate in patients with stable coronary artery disease (CAD). METHODS AND RESULTS We assessed the relationship between resting heart rate at baseline and cardiovascular mortality/morbidity, while adjusting for risk factors. A total of 24 913 patients wi...

(1) Background: We assessed the effect of moxifloxacin on heart rate, and reviewed the heart rate effects of other antibiotics; (2) Methods: A total of 335 normal volunteers had 12-lead electrocardiograms recorded at multiple time points before and during treatment with moxifloxacin and with placebo in seven consecutive, thorough QT studies of crossover design; (3) Results: The average baseline...

The objective of the present study was to evaluate the influence of posture on the responses of blood pressure (BP) and heart rate (HR) to the Valsalva manoeuvre (VM). Neurohumoral activation, as well as changes in intravascular and intracardiac volumes and pressures, are well known effects of orthostatic stress. These changes are likely to have significant effects on cardiovascular reflexes, s...

introduction: among infants hospitalized in the neonatal intensive care unit, excessive noise is correlated with increases in heart rate, increase in respiratory rate, decrease in oxygen saturation a s well as sleep disturbances. apart from overcoming the noise in the environment, music is believed to enhance the infant’s general well-being, reduce its stress and   unpleasant symptoms. this stu...

Conventional spectral analyses of heart rate variability (HRV) have been limited to stationary signals and have not allowed the obtainment of information during transient autonomic cardiac responses. In the present study, we evaluated the ability of the short-time Fourier transform (STFT) method to detect transient changes in vagal effects on the heart. We derived high-frequency power (HFP, 0.2...

Fourteen Spinal Cord Injured (SCI) and 15 Ablebodied (AB) individuals participated in two 30 minutes (min) standing sessions. The control groups (SCICONT, ABCONT) consisted of both AB and SCI standing still with no muscle contraction. The experimental groups consisted of both SCI subjects (SCIEXP) standing with use of Functional Electrical Stimulation (FES)-induced muscle activation of four low...

In this study, the relation between the measurement duration and accuracy of pulse-counting was quantitatively examined with special reference to low-frequency fluctuations in heart rate variability. The interbeat intervals of 70 healthy male subjects were measured in standing, sitting and supine positions. Pulse rates for various durations were calculated by objective-scoring simulation based ...

AIMS Increased afterload in idiopathic pulmonary arterial hypertension (IPAH) causes right ventricular (RV) hypertrophy and failure. Since RV remodelling occurs with alterations in RV oxygen metabolism, increasing our understanding in the factors determining RV O(2) consumption in IPAH is necessary. In the left ventricle, it is known that heart rate and systolic blood pressure are the main dete...