Bile acid sequestrants have been shown to reduce glucose levels in patients with type 2 diabetes. We previously reported that the bile acid sequestrant colesevelam HCl (Welchol) (COL) induced the release of glucagon-like peptide (GLP)-1 and improved glycemic control in insulin-resistant rats. In the present study, we tested whether adding sitagliptin (Januvia) (SIT), which prolongs bioactive GL...

After cardiac catheterisation, haemostasis is usually achieved by manual compression of the puncture site. The patient is then laid flat, allowed to sit up and then to mobilise—a process taking considerably longer than the procedure itself, and possibly involving more prolonged bed occupancy than is necessary. Well conducted, randomised, controlled trials of patient position (supine or upright)...

The present study examined whether a sit-to-stand score can be related to the force-generating capacity of knee extensor muscles. Fifty-seven subjects (28 men, 63.0+/-7.8 yrs, and 29 women, 64.2+/-7.5 yrs, means+/-SDs) performed a 10-repeated sit-to-stand test as fast as possible, on a steel molded chair. The time taken (T(sit-stand)) was measured with a manual stopwatch. The leg length (L), de...

Abstract Research over the past decade has demonstrated that dynamical forecast systems can skillfully predict pan-Arctic sea ice extent (SIE) on seasonal time scale; however, there have been fewer assessments of prediction skill user-relevant spatial scales. In this work, we evaluate regional Arctic SIE predictions made with Forecast-Oriented Low Ocean Resolution (FLOR) and Seamless System for...

This paper presents an approach of identifying prosthetic knee movements through pattern recognition of mechanical responses at the internal socket's wall. A quadrilateral double socket was custom made and instrumented with two force sensing resistors (FSR) attached to specific anterior and posterior sites of the socket's wall. A second setup was established by attaching three piezoelectric sen...

Introduction: Smell Identification Tests (SIT) are routinely utilized for the clinical evaluation of olfactory function. Since Iran consists of various ethnic subgroups, the reliability and validity of this test as a national SIT are required to be evaluated across the country.   Materials and Methods: This cross-sectio...

BACKGROUND The sit and reach test is the most common flexibility test used in health related fitness test batteries. OBJECTIVE To examine and compare three different sit and reach tests as a measure of hamstring flexibility in 102 female students. METHOD The traditional sit and reach test, the chair sit and reach test, the back saver sit and reach test, and passive straight leg raise were a...