eveloping cell lines for use as accurate models for disease has always been a challenging task. In order to replicate phenotypes or enable downstream experimentation, genome engineering of cell lines is required. Techniques enabling genome modification have evolved over a number of years, from simple viral vectors used to insert sequences in random locations, to more sophisticated methods that ...

A brief review presents current data on the possibilities of predicting course cardiovascular and other diseases, as well results surgical treatment in patients by assessing concentration atrial, brain natriuretic peptides, polymorphic gene variants these peptides their receptors. Significant prospects for further research this direction have been identified order to develop prognostic molecula...