Silymarin is an antihepatotoxic substance isolated from fruits of Silybum marianum. Possibly due to their antioxidant and membrane stabilizing properties, the compounds have been shown to protect different organs and cells against a number of insults. The content and composition of main silymarin components (silybin, isosilybin, silydianin and silychristin) in various pharmaceuticals were analy...

In present report effects of explants type, basal media and plant growth regulators (PGRs) were tested for induction of indirect somatic embryogenesis in medicinally important plant Silybum marianum L. Leaf, petiole and root explants were exploited in vitro on B5 (Gamborg), SH (Schenk and Hildebrandt) and MS (Murashige and Skoog) media for induction of embryogenic callus followed by somatic emb...

Background and objectives: Silymarin is a unique flavonoid complex with documented hepatoprotective properties. Silybum marianum hairy root culture as a source for producing silymarin has been an important strategy for study the cell signaling pathway. In the present investigation Trichoderma strainsSilybum marianum hairy root cultures interactions have been studied. Methods: The effects of two...

this experiment was conducted to evaluate the ability of silybum marianum seeds (sms) on performance, carcass variables, and liver morphology of the broiler chickens contaminated with aflatoxin b1 (afb1). a total of 216 broiler chicks (ross 308) were used. birds were randomly assigned to nine treatment groups, with four replicates and six birds in each replicate. chickens were reared on litter ...

background & aim: increasing of drug resistances and more attention to the hazards of side effects of synthetic drugs has caused extensive researches on medicinal plant resources. the aim of this study was to determination of the chemical composition of native silybum marianum and foeniculum vulgare extractions in ardabil, iran; and investigation of their anticancer effect on liver cancer cell ...