The role of B1 in the dual nature of ARS in Saccharomyces cerevisiae Patricia Chisamore-Robert Advisor: University of Guelph, 2012 Dr. K Yankulov In Saccharomyces cerevisiae, DNA replication initiates at distinct origins termed Autonomously Replicating Sequences (ARSs). A key element in ARS is the ACS/B1 sequence, which binds the Origin Recognition Complex (ORC). During early G1 phase, the pre-...

The enhancer elements from either simian virus 40 or murine sarcoma virus activate the expression of a transfected rat insulin 1 (r11) gene when placed within 2.0 kilobases or less of the rl1 gene cap site. Inclusion of 4.0 kilobases of upstream r11 sequence, however, results in a substantial reduction in the enhancer-dependent insulin gene expression. These observations suggested that a negati...

abstract background: given the fact of irrecoverable consequences of noise in industrial societies and the environment, acoustic filter (silencer) is an instrument which obstacles the transmission of sound waves. a sort of this silencer is helmholtz resonator (branch amplifier) which comes to sound appropriate for low and below 200 hz frequencies in fan and channel noise. the purpose of this ar...

PURPOSE To localize cis-acting elements involved in the expression of the cone-specific G-protein, cone transducin alpha-subunit (GNAT2). METHODS In this study, the authors used a genomic clone, HGLG3, to sequence 3139 base pairs of the upstream region of the GNAT2 gene and to localize cis-acting elements involved in the expression of GNAT2. Upstream elements were localized functionally by tr...