Abstract Background and Objective: According to the issue of dependence and tolerance in addicted patients, the inefficiency of existing treatments and the new recommendation for drug combination therapy for diseases in modern pharmacology, the present study examined the effect of methadone and valproate combination on morphine dependence and tolerance. Materials and Methods: Ninety-eight male ...

Abstract: Coccidiosis is one of the major parasitic diseases of poultry. In this study, to compare the effects of coccidiostatic drugs on fecal oocyst shedding and body weight gain of coccidi-infected broiler chickens, 180 one day old Ross 308 broiler chicks were randomly assigned to four treatments. Each treatment contained 3 replicates of 15 chickens. Treatments 1 and 2 were fed diets supplem...

This experiment was carried out to evaluate different levels of peppermint (Mentha piperita) plant powder usage on feed conversion ratio (FCR), body weight (BW), feed intake (FI), body temperature, carcass parts (breast and thigh) and internal organs (liver, heart, gizzard) weights in broiler chicken. A total of 192 broiler chicken were randomly divided into 4 experimental treatments with 4 rep...

morphine withdrawal usually results in unsuccessful outcomes. despite partial benefits from alternative substances such as methadone, its use may not lead to the desired result due to the lack of mental tranquility during the withdrawal period. in this study, by means of an animal model, morphine itself was used to manage morphine dependence. forty mice were divided into 5 groups, in which 4 gr...

an experiment was conducted to evaluate the effect of early feed restriction on performance and serum thyroxin concentration of broiler chicks. the experiment was designed in a 2×2 factorial with 5 replicates of floor pens with 12 male or female chicks in each. 240 male and/or female day-old chicks of a commercial strain (hybrow) were wing banded, weighed and randomly allocated to two treatment...

BACKGROUND The aim of the study is to investigate the healing effect of the bone-marrow derived mesenchymal stem cells (BM-MSCs) on ischemic colon anastomosis in systemic application and to recovery the adverse effect of ischemia. MATERIALS AND METHODS Fourty male Wistar Albino rats weigthing 250-300 g were divided into four equal groups (n=10 Group 1: control; ischemic left colonic anastomos...

This study was done to evaluate the antimicrobial and antioxidant effects of nisin Z (0.02 %) and sodium benzoate (1.5 and 2.5 %) in vacuum packed Caspian Kutum (Rutilus frisii) fillet stored at 4°C. Microbial changes [aerobic plate counts (APC), psychrotrophic counts (PTC) and lactic acid bacteria] and chemical indices [peroxide value and total volatile basic nitrogen (TVB-N)] were determined ...

This study was done to evaluate the antimicrobial and antioxidant effects of nisin Z (0.02 %) and sodium benzoate (1.5 and 2.5 %) in vacuum packed Caspian Kutum (Rutilus frisii) fillet stored at 4°C. Microbial changes [aerobic plate counts (APC), psychrotrophic counts (PTC) and lactic acid bacteria] and chemical indices [peroxide value and total volatile basic nitrogen (TVB-N)] were determi...

introduction: calcium/calmodulin-dependent protein kinase ii (camkii) is highly expressed in the hippocampus, which has a pivotal role in reward-related memories and morphine dependence. methods: in the present study, morphine tolerance was induced in male wistar rats by 7 days repeated morphine injections once daily, and then gene expression profile of α-isoform of camkii (camkiiα) in the hipp...