نتایج جستجو برای: sibutramine
تعداد نتایج: 486 فیلتر نتایج به سال:
BACKGROUND In response to the increase in obesity, pharmacologic treatments for weight loss have become more numerous and more commonly used. PURPOSE To assess the efficacy and safety of weight loss medications approved by the U.S. Food and Drug Administration and other medications that have been used for weight loss. DATA SOURCES Electronic databases, experts in the field, and unpublished ...
To the Editor: Sibutramine is a potent serotonin-norepinephrine reuptake inhibitor that was approved by the US Food and Drug Administration (FDA) in 1997 for the treatment of obesity. 1,2 In 2010, the FDA issued a voluntary withdrawal of the drug due to concerns over adverse cardiovascular effects. 3,4 Despite this, sibutramine continues to be found in herbal slimming products sold over the Int...
AIMS Obesity causes a high disease burden in Australia and across the world. We aimed to analyse the cost-effectiveness of weight reduction with pharmacotherapy in Australia, and to assess its potential to reduce the disease burden due to excess body weight. METHODS We constructed a multi-state life-table based Markov model in Excel in which body weight influences the incidence of stroke, isc...
This review provides a comparative analysis of the benefits of lifestyle intervention and pharmacotherapy in adults and children using previously published meta-analyses, as well as new data published within the past 2 years. The manuscript critically summarizes the potential risks of various established (orlistat, sibutramine, and metformin) and new (rimonabant) pharmacologic agents and presen...
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