We employ Lasso shrinkage within the context of sufficient dimension reduction to obtain a shrinkage sliced inverse regression estimator, which provides easier interpretations and better prediction accuracy without assuming a parametric model. The shrinkage sliced inverse regression approach can be employed for both single-index and multiple-index models. Simulation studies suggest that the new...

In this paper a new wavelet shrinkage technique is proposed and investigated. When data consist of a multiplicity of related noisy signals, we propose a wavelet-based shrinkage estimation procedure to summarize all data components into a single regularized and representative signal (\base-line"). This fusion of information from di erent runs is done via Stein-type shrinkage rule resulting from ...

Activity-induced modification of neuronal connections is essential for the development of the nervous system and may also underlie learning and memory functions of mature brain. Previous studies have shown an increase in dendritic spine density and/or enlargement of spines after the induction of long-term potentiation (LTP). Using two-photon time-lapse imaging of dendritic spines in acute hippo...

Estimation of the mean function in nonparametric regression is usefully separated into estimating the means at the observed factor levels—a one-way layout problem— and interpolation between the estimated means at adjacent factor levels. Candidate penalized least squares (PLS) estimators for the mean vector of a one-way layout are expressed as shrinkage estimators relative to an orthogonal regre...

OBJECTIVES To investigate the influence of pre-heating of high-viscosity bulk-fill composite materials on their degree of conversion and shrinkage force formation. METHODS Four bulk-fill composite materials (Tetric EvoCeram Bulk Fill-TECBF, x-tra fil-XF, QuixFil-QF, SonicFill-SF) and one conventional nano-hybrid resin composite (Tetric EvoCeram-TEC) were used. The test materials were either k...

BACKGROUND The long-acting somatostatin analogue octreotide is used either as an adjuvant or primary therapy to lower growth hormone (GH) levels in patients with acromegaly and may also induce pituitary tumor shrinkage. OBJECTIVE We performed a meta-analysis to accurately assess the effect of octreotide on pituitary tumor shrinkage. DATA SOURCES A computerized Medline and Embase search was ...

BACKGROUND After resection, specimens are subjected to formalin fixation during histological processing. This procedure can result in tissue shrinkage, with the amount of shrinkage related to tissue composition and tissue type. AIMS To evaluate the shrinkage of nasal mucosa and cartilage tissue and compare differences in shrinkage after resection, after formalin fixation, and during microscop...

The drying kinetics of hawthorn in a pilot-scale experimental fluidized bed dryer with and without vibration was investigated. The effect of operating parameters, such as vibration intensity, drying air flow rate, and temperature, on the drying rate and shrinkage of hawthorn was studied. The hawthorn fruit was dried at various drying air temperatures ranging from 40-70oC and drying air volume f...

Background: Surgical margin determination in malignant lesions is essential and has a direct impact on the choice of postoperative treatments and patient follow-up. Therefore, the processes affecting this variable are worth exploring. This study aimed to evaluate the difference in surgical margin values in excisional skin samples during surgery and after formalin fixation. Methods: A cross-sec...