The last decade has seen many trials with antioxidants in patients with cardiovascular disease, with equivocal results. One possible explanation for the disappointing findings is the lack of identification criteria of patients who are potential candidates for antioxidant treatment. Several studies have been carried out in patients at risk of cardiovascular disease, indicating that enhanced oxid...

Recent debate and cases involving elite athletes raised the question whether or not Cannabis sativa (cannabis) should be considered doping in sports. Results from a 2010 report in the United States (Substance Abuse and Mental Health Services Administration, 2011) showed that cannabis is the most used illicit drug, with 17.4 million users smoking cannabis and 6.9 million users smoking cannabis o...

OBJECTIVE To evaluate how the ranking of IVF programs changes if high-order multiple pregnancies (HOMPs) are considered negative outcomes. DESIGN Retrospective analysis. SETTING The 2004 Society for Assisted Reproductive Technology Clinic Outcome Reporting System. PATIENT(S) Two hundred seven programs that performed >50 IVF cycles were analyzed, and only patients <or=35 years of age were ...

Lifelong low-phenylalanine (Phe) dietary management is the foundation of care in phenylketonuria (PKU). However, strict monitoring of food intake places a burden on patients and their caregivers, and adherence to the required diet frequently decreases in later childhood and adolescence. Rarely, parents of children with PKU refuse to recognise the importance of treatment and follow-up for this c...

A 17-year-old female was admitted to our emergency room 30 min after suicidal ingestion of about 10 g Tramadol. The patient had several short-lived clonic seizures before admission. On arrival, she had an episode of tonic-clonic seizure, lasting for three minutes, which lead to cardiopulmonary arrest after administration of 10 mg diazepam intravenously. Endotracheal intubation and cardiopulmona...