Urinary cells obtained from voided urine specimens of 46 patients with urothelial carcinomas (UCs) and 10 normal individuals were analyzed with 3 different centromeric fluorescence in situ hybridization (FISH) probes. The overall sensitivity of cytology was 48.9% compared to 95.7%with the FISH technique. The minimum values were found for stage Ta and grade 1 (90.5 and 89.4) and sensitivity of F...

Frog sex chromosomes offer an ideal system for advancing our understanding of genome evolution and function because of the variety of sex determination systems in the group, the diversity of sex chromosome maturation states, the ease of experimental manipulation during early development. After briefly reviewing sex chromosome biology generally, we focus on what is known about frog sex determina...

The incidence of males with an XYY chromosome complement in a maximum security hospital was found to be 3% (Jacobs et al., 1965). These males were exceptionally tall, and it was found that 1 in 3 of the men of over 6 ft. (183 cm.) in this hospital had an XYY chromosome constitution. This very high incidence in an over-6 ft. group was confirmed in a special hospital for the subnormal (Casey et a...

The incidence of males with an XYY chromosome complement in a maximum security hospital was found to be 3% (Jacobs et al., 1965). These males were exceptionally tall, and it was found that 1 in 3 of the men of over 6 ft. (183 cm.) in this hospital had an XYY chromosome constitution. This very high incidence in an over-6 ft. group was confirmed in a special hospital for the subnormal (Casey et a...

BACKGROUND Male infertility is responsible for 50% of infertile couples. Thirty percent of male infertility is due to cytogenetic and genetic abnormalities. In Arab and North African populations, several studies have shown the association of these chromosomal abnormalities with male infertility. Our objective is to evaluate the frequency of chromosomal abnormalities and Y chromosome microdeleti...

The incidence of males with an XYY chromosome complement in a maximum security hospital was found to be 3% (Jacobs et al., 1965). These males were exceptionally tall, and it was found that 1 in 3 of the men of over 6 ft. (183 cm.) in this hospital had an XYY chromosome constitution. This very high incidence in an over-6 ft. group was confirmed in a special hospital for the subnormal (Casey et a...