نتایج جستجو برای: serum il 17
تعداد نتایج: 681510 فیلتر نتایج به سال:
Background and Aims: Natural killer T (NKT) cells have been suggested to play critical roles in a wide range of immune responses especially against hepatotropic pathogens such as hepatitis C virus (HCV). In the present study, we investigated the status of NKT cells by producing interleukin-17 cytokine in peripheral bl...
T-helper (Th) 22 and Th17 cells are involved in the pathogenesis of autoimmune diseases. However, their roles in the pathogenesis of Graves'disease (GD) are unclear. This study is aimed at examining the frequency of peripheral blood Th22, Th17, and Th1 cells and the levels of plasma IL-22, IL-17, and IFN-γ in patients with GD. A total of 27 patients with new onset GD and 27 gender- and age-matc...
Interleukin-17A (IL-17) promotes inflammatory renal tissue damage in mouse models of crescentic glomerulonephritis, including murine experimental autoimmune anti-myeloperoxidase glomerulonephritis, which most likely depends on IL-17-producing Th17 cells. In human anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis, however, the cellular sources of IL-17 remain to be elucid...
The study of pathogenic systems involved in multiple sclerosis (MS) is essential for the development new therapies. Objective : to determine contribution B-lymphocytes production IL-17 MS with an assessment ability B-cells induce differentiation Th17 and own by this pathology. Material methods . A total 81 subjects were examined, 68 whom patients diagnosed MS, 13 healthy individuals. concentrat...
Background: Th2 immune responses are linked primarily to mild and moderate asthma, while Th17 cells, Interleukin-17A (IL-17) and neutrophilia have been implicated in more severe forms of disease. How Th2-dependent allergic reactions are influenced by Th17 and IL-17-γδ T cells is poorly understood. In murine models, under some conditions, IL-17 promotes Th2-biased airway inflammatory responses. ...
Background Rheumatoid arthritis (RA) is an autoimmune inflammatory driven by cascade of different cytokine families. IL-23/Th17 axis (IL-23, IL-17) has been studied as a key pathway for disease development and its association with severity, joint erosion functional outcome [1], but the data supplementing to support hypothesis lacking conflicting. Also, there paucity on role IL-23/Th17/IL-17 cyt...
objective: th17 cells are known to be involved in some types of inflammations and autoimmune disorders. rorc2 is the key transcription factor coordinating th17 cell differentiation. thus, blocking rorc2 may be useful in suppressing th17-dependent inflammatory processes. the aim was to silence rorc2 by specific sirnas in naïve t cells differentiating to th17. time-dependent expression of rorc2 a...
objective(s): systemic lupus erythematosus (sle) is a multi-factorial autoimmune disease which may be characterized by t lymphocytes dysfunctions. th17 cells have been identified as new effector cells, which play an important role in the pathogenesis. in recent years, immunomodulatory effect of vitamin d3 has been noticed. in the present experiment, the effect of vitamin d3 on the expression of...
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