نتایج جستجو برای: serum il 17

تعداد نتایج: 681510  

Background and Aims: Natural killer T (NKT) cells have been suggested to play critical roles in a wide range of immune responses especially against hepatotropic pathogens such as hepatitis C virus (HCV). In  the  present  study,  we  investigated  the  status  of  NKT  cells  by producing interleukin-17 cytokine in  peripheral  bl...

2013
Di Peng Bingchuan Xu Ye Wang Hui Guo Yanfang Jiang

T-helper (Th) 22 and Th17 cells are involved in the pathogenesis of autoimmune diseases. However, their roles in the pathogenesis of Graves'disease (GD) are unclear. This study is aimed at examining the frequency of peripheral blood Th22, Th17, and Th1 cells and the levels of plasma IL-22, IL-17, and IFN-γ in patients with GD. A total of 27 patients with new onset GD and 27 gender- and age-matc...

Journal: :American journal of physiology. Renal physiology 2012
Joachim Velden Hans-Joachim Paust Elion Hoxha Jan-Eric Turner Oliver M Steinmetz Gunter Wolf Wolfram J Jabs Fedai Özcan Joachim Beige Peter J Heering Saskia Schröder Ursula Kneißler Erik Disteldorf Hans-Willi Mittrücker Rolf A K Stahl Udo Helmchen Ulf Panzer

Interleukin-17A (IL-17) promotes inflammatory renal tissue damage in mouse models of crescentic glomerulonephritis, including murine experimental autoimmune anti-myeloperoxidase glomerulonephritis, which most likely depends on IL-17-producing Th17 cells. In human anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis, however, the cellular sources of IL-17 remain to be elucid...

Journal: :Nevrologiâ, nejropsihiatriâ, psihosomatika 2023

The study of pathogenic systems involved in multiple sclerosis (MS) is essential for the development new therapies. Objective : to determine contribution B-lymphocytes production IL-17 MS with an assessment ability B-cells induce differentiation Th17 and own by this pathology. Material methods . A total 81 subjects were examined, 68 whom patients diagnosed MS, 13 healthy individuals. concentrat...

2014
Emily M Nakada Jichuan Shan Margaret W Kinyanjui Elizabeth D Fixman

Background: Th2 immune responses are linked primarily to mild and moderate asthma, while Th17 cells, Interleukin-17A (IL-17) and neutrophilia have been implicated in more severe forms of disease. How Th2-dependent allergic reactions are influenced by Th17 and IL-17-γδ T cells is poorly understood. In murine models, under some conditions, IL-17 promotes Th2-biased airway inflammatory responses. ...

Journal: :Annals of the Rheumatic Diseases 2023

Background Rheumatoid arthritis (RA) is an autoimmune inflammatory driven by cascade of different cytokine families. IL-23/Th17 axis (IL-23, IL-17) has been studied as a key pathway for disease development and its association with severity, joint erosion functional outcome [1], but the data supplementing to support hypothesis lacking conflicting. Also, there paucity on role IL-23/Th17/IL-17 cyt...

Journal: :cell journal 0

objective: th17 cells are known to be involved in some types of inflammations and autoimmune disorders. rorc2 is the key transcription factor coordinating th17 cell differentiation. thus, blocking rorc2 may be useful in suppressing th17-dependent inflammatory processes. the aim was to silence rorc2 by specific sirnas in naïve t cells differentiating to th17. time-dependent expression of rorc2 a...

Journal: :iranian journal of basic medical sciences 0
fatemeh faraji immunology research center, buali research institute, school of medicine, mashhad university of medical sciences, mashhad, iran maryam rastin immunology research center, buali research institute, school of medicine, mashhad university of medical sciences, mashhad, iran fahimeh lavi arab immunology research center, buali research institute, school of medicine, mashhad university of medical sciences, mashhad, iran mohammad reza kalantari pathology department, ghaem hospital, school of medicine, mashhad university of medical sciences, mashhad, iran shahrzad zamani taghizadeh rabe immunology research center, buali research institute, school of medicine, mashhad university of medical sciences, mashhad, iran nafise tabasi immunology research center, buali research institute, school of medicine, mashhad university of medical sciences, mashhad, iran

objective(s): systemic lupus erythematosus (sle) is a multi-factorial autoimmune disease which may be characterized by t lymphocytes dysfunctions. th17 cells have been identified as new effector cells, which play an important role in the pathogenesis. in recent years, immunomodulatory effect of vitamin d3 has been noticed. in the present experiment, the effect of vitamin d3 on the expression of...

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