This cross-sectional study was designed to examine the prevalence of adrenocortical suppression in children with asthma treated with high-dose inhaled fluticasone propionate (FP). Children and adolescents (n=50) with asthma, treated with inhaled FP at a dose of > or = 1,000 mg a day for > or = 6 months, were enrolled. Early morning serum cortisol was performed. Subjects with a serum cortisol of...

UNLABELLED Cushing syndrome is a hormonal disorder caused by prolonged exposure of body tissue to cortisol. We report two cases of iatrogenic Cushing's syndrome in two Nigerian children following intranasal administration of aristobed-N (Betamethasone + Neomycin) given at a private hospital where the children presented with feature of adenoidal hypertrophy. Two months into treatment children we...

The temporal relationship between administration of cortisol and serum 17alpha-hydroxyprogesterone was investigated in five patients aged 9-19 years with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. There was marked variability in the 17alpha-hydroxyprogesterone response (determined hourly for 24 h) of individual patients to administration of cortisol. Mean concentration was...

Human serum albumin (HSA) is an important protein that carries variety of substances like some hormones and drugs in blood. Pharmacological studies of the interaction of many drugs and HSA are reported during several decades, specially recently years. Interaction of cortisol and fluoxetine hydrochloride (FLX) (as a common anti-stress drug) with HSA (as their carrier in blood) has been studied s...

Background Obstructive sleep apnea syndrome (OSAS) may be associated with an increase in hypothalamic-pituitary-adrenocortical axis activity (HPA AA). We reviewed research comparing morning salivary and blood (serum plasma) cortisol concentrations of individuals OSAS to those healthy controls. Methods made a systematic search without any restrictions the PubMed/Medline, Scopus, Cochrane Library...

Welfare assessment of dairy calves is commonly conducted through the observation their behavior and analysis physiological parameters. Despite large number studies on this topic, there a lack research possible correlation between parameters at basal level in calves. For reason, present study aimed to investigate correlations serum cortisol, neutrophil-to-lymphocyte ratio (N/L) locomotor play 21...

BACKGROUND The effect of etomidate administration on the adrenal cortex in obese patients is still unclear. The objective of the study was to determine the influence of a single dose of etomidate on cortisol secretion in the morbidly obese. METHODS 127 healthy patients were enrolled into the study. Data from 82 patients scheduled for elective laparoscopic surgery were analyzed. 62 of them wer...

The aim of the study was to evaluate hormonal responses of serum cortisol, growth hormone (GH), testesterone and insulin-like growth factor-1 (IGF-1) levels during dynamic and static stress exercises in 20 male volunteer student athletes. The serum fasting hormonal levels of the participants were measured after six weeks of general resistance exercise. Subsequently, nine of the participants per...

In normal use, milking parlor can cause the release of oxytocin through neuroendocrine reflex, but the use of milking parlor sometimes cause stress and lead to a decrease in milk production. In Indonesia at this time, traditional milking by hand is still widely used by dairy farmers. The purpose of this study is to investigate the use of milking parlor to the physiological and behavioral respon...

BACKGROUND Normative data have been established for stimulated serum total cortisol in children but not for serum free cortisol. METHODS Children who were referred for ACTH testing to rule out adrenal insufficiency were enrolled. Only children with normal response and normal androgen levels were included. Total cortisol was determined by a chemiluminescence method, and free cortisol was measu...