Histopathological alterations in the liver of intermediated hosts infected with Echinococcus granulosus parasite can be occurred by necrotic expansion as a result an increase growth larva stage (metacestode), which may cause perturbation production function markers. Thus, this study aims to determinate biochemical profile and some serum electrolytes E. granulosus-infected sheep at different hyd...

Background The changes in bone metabolism may occur earlier than those that can be identified on radiography. Although studies have evaluated the inflammatory markers precede radiographic progression, no relationship between timing of and progression patients with AS. Objectives To determine serum alkaline phosphatase levels over time ankylosing spondylitis. Methods This retrospective study ele...

BACKGROUND Calcitriol is documented to cause significant increase in bone mass densitometry counteracting osteoporosis. Promising results of calcitriol supplementation in studies aiming space flight induced osteoporosis is little and the effect of this hormone on biomarkers of bone metabolism is not examined yet in space flight models of osteoporosis in rats. METHODS This was an interventiona...

Background: Alkaline phosphatase (ALP), (EC 3.1.3.1) is a hydrolase enzyme responsible for removing phosphate groups from various molecules in the body. In humans, ALPis present in all tissues such as liver, bile duct, kidney, bone, and the placenta which detection of its activity is so useful in molecular biology. Pregnancy is associated with normal physiological changes that assist fetal surv...

The effect of aqueous extract of Hibiscus sabdariffa L. on the activity of alkaline phosphatase and uric acid in the liver of Rattus novergicus was studied in this research. The result from this study revealed that the activities of alkaline phosphatase in the serum slightly increased (18.00±3.39) when compared with that of the control (16.37±3.50) at (P<0.05) (Table. 1), though this was not st...

BACKGROUND Abnormalities in serum alkaline phosphatase (ALP) and intact parathyroid hormone (PTH) concentrations, as biochemical markers of bone turnover in dialysis patients, correlate with increased mortality in maintenance hemodialysis (MHD) patients. Changes in bone turnover rate vary with age. The mortality predictability of serum ALP and PTH levels in MHD patients may be different across ...

ABSTRACT. An electrochemical assay of the enzyme alkaline phosphatase (ALP) using ascorbic acid 2-phosphate (AAP) as a new voltammetric substrate has been described in this paper. In the alkaline buffer solution the ALP enzymatic hydrolysis product of AAP was ascorbic acid (AA), which was an electro-active substance and had a sensitive differential pulse voltammetric (DPV) oxidative response on...

To separate liver and bone alkaline phosphatase (ALP) isoenzymes in human serum, we used high-performance affinity chromatography (HPAC) on a column of wheat-germ lectin conjugated to 7-microns-diameter silica particles and an eluent containing N-acetyl-D-glucosamine (NAG). On-line spectrophotometric detection of ALP involved pumping diethanolamine-buffered p-nitrophenyl phosphate solution post...

Background & AimsGamma-glutamyltransferase (GGT) is a serum marker of cholestasis. We investigated whether level GGT prognostic for patients with primary biliary cholangitis (PBC).MethodsWe analyzed data from PBC the Global Study Group, comprising 14 centers in Europe and North America. obtained measurements at baseline time points after treatment. used Cox model hazard ratios to evaluate assoc...

homalium letestui pellegr (flacourtiaceae) is used traditionally by the ibibios of southern nigeria to treat stomach ulcer, malaria and other inflammatory diseases and yorubas of western nigeria as an antidote. the hepatoprotective effect of the stem extract (200-600 mg/kg) was evaluated by the assay of liver function parameters, namely total and direct bilirubin, serum protein and albumin, tot...