BACKGROUND Sensory gating, often described as the ability to filter out irrelevant information that is repeated in close temporal proximity, is essential for the selection, processing, and storage of more salient information. This study aimed to test the effect of sensory gating under anesthesia in the prefrontal cortex (PFC) of monkeys following injection of bromocriptine, haloperidol, and phe...

An ANN is an information processing paradigm that is inspired by the way biological nervous system, mainly human and primates, process sensory information. It is proposed in that environmental information in biological central nervous system (CNS) undergoes three processing stages as shown in Figure 1, (Arbib, 2003; Haykin, 2003; Dayan, & Abbot, 2001). 1. Conversion into encoded electrical sign...

All physical systems must reliably extract information from their noisily and partially observable environment, such as distances to objects. Biology has developed reliable mechanisms to combine multi-modal sensory information into a coherent belief about the underlying environment that caused the percept; a process called sensor fusion. Autonomous technical systems (such as mobile robots) empl...

Pain is a uniquely individual experience that is heavily shaped by evaluation and judgments about afferent sensory information. In visual, auditory, and tactile sensory modalities, evaluation of afferent information engages brain regions outside of the primary sensory cortices. In contrast, evaluation of sensory features of noxious information has long been thought to be accomplished by the pri...

In this perspective, we propose the absence of detailed information regarding spinal cord circuits that process sensory information remains a major barrier to advancing analgesia. We highlight recent advances showing that functionally discrete populations of neurons in the spinal cord dorsal horn (DH) play distinct roles in processing sensory information. We then discuss new molecular, electrop...

It is clear that the information processed by the different sensory modalities are integrated into a coherent multisensory percept by the brain. However, it is not known how, nor at what level of processing, nor where in the brain this integration takes place. As a result, it is also not clear whether the combination of signals from different modalities occurs prior to or following conscious se...

Where do the bottlenecks for information and attention lie when our visual system processes incoming stimuli? The human visual system encodes the incoming stimulus and transfers its contents into three major memory systems with increasing time scales, viz., sensory (or iconic) memory, visual short-term memory (VSTM), and long-term memory (LTM). It is commonly believed that the major bottleneck ...

UNLABELLED As we learn about items in our environment, their neural representations become increasingly enriched with our acquired knowledge. But there is little understanding of how network dynamics and neural processing related to external information changes as it becomes laden with "internal" memories. We sampled spiking and local field potential activity simultaneously from multiple sites ...

Sensory information entering the nervous system follows independent paths of processing such that specific features are individually detected. However, sensory perception, awareness, and cognition emerge from the combination of information. Here we have analyzed the corticocortical network of the cat, looking for the anatomical substrate which permits the simultaneous segregation and integratio...