Background: Households are important elements in food disaster preparedness and play role its management. This study compared household food-prone rural urban communities Kaduna State.
 Methods: The comparative cross-sectional was conducted among households foodprone 2019. population were heads. sample size for the 202 each communities. Respondents selected by multi- stage sampling techniq...

Objectives. The purpose of this study was to collect data on self-reported sharps injuries to develop best practices to reduce them. Methods. Data on sharps injuries were collected for the period of January-October 2008 using Adverse Event Notification Forms already in use at Sema Hospital. Results. On average, 0.2% of all self-reported injuries were sharps injuries averaging one injury per mon...

Central nervous system (CNS) has a highly specialized microenvironment, and despite being initially considered an immune privileged site, this immune status is far from absolute because it varies with age and brain topography. The brain monitors immune responses by several means that act in parallel; one pathway involves afferent nerves (vagal nerve) and the other resident cells (neurons and gl...

Improving osseointegration of extensively used titanium (Ti) implants still remains a main theme in implantology. Recently, grafting biomolecules onto a Ti surface has attracted more attention due to their direct participation in the osseointegration process around the implant. Semaphorin 3A (Sema3A) is a new proven osteoprotection molecule and is considered to be a promising therapeutic agent ...

Plexin receptors play a crucial role in the transduction of axonal guidance events elicited by semaphorin proteins. In Drosophila, Plexin A (PlexA) is a receptor for the transmembrane semaphorin semaphorin-1a (Sema-1a) and is required for motor and central nervous system (CNS) axon guidance in the developing embryonic nervous system. However, it remains unknown how PlexB functions during neural...

Artificial intelligence (AI) is progressing rapidly, and in this trend, edge AI has been researched intensively. However, much less work performed around the security of AI. Machine learning models are a mass intellectual property, an optimized network very valuable. Trained machine need to be black boxes as well because they may give away information about training data outside world. As selec...

Epistasis is an important feature of the genetic architecture of quantitative traits, but the dynamics of epistatic interactions in natural populations and the relationship between epistasis and pleiotropy remain poorly understood. Here, we studied the effects of epistatic modifiers that segregate in a wild-derived Drosophila melanogaster population on the mutational effects of P-element insert...

The generation of a functional nervous system is dependent on precise pathfinding of axons during development. This pathfinding is directed by the distribution of local and long-range guidance cues, the latter of which are believed to be distributed in gradients. Gradients of guidance cues have been associated with growth cone function for over a hundred years. However, little is known about th...

Axon regeneration is arrested in the injured central nervous system (CNS) by axon growth-inhibitory ligands expressed in oligodendrocytes/myelin, NG2-glia, and reactive astrocytes in the lesion and degenerating tracts, and by fibroblasts in scar tissue. Growth cone receptors (Rc) bind inhibitory ligands, activating a Rho-family GTPase intracellular signaling pathway that disrupts the actin cyto...

BACKGROUND GABAergic interneurons regulate the balance and dynamics of neural circuits, in part, by elaborating their strategically placed axon branches that innervate specific cellular and subcellular targets. However, the molecular mechanisms that regulate target-directed GABAergic axon branching are not well understood. RESULTS Here we show that the secreted axon guidance molecule, SEMA3A,...