s mixed-signal systems, by integrating digital and analog components in a homogeneous virtual platform model for efficient simulation. This can be achieved thanks to: 1) an automatic abstraction technique for analog components, allowing to preserve only the details meaningful for the functional behavior of the entireion technique for analog components, allowing to preserve only the details mean...

Peroxidases are enzymes catalyzing redox reactions that cleave peroxides. Their active redox centers have heme, cysteine thiols, selenium, manganese, and other chemical moieties. Peroxidases and their mimetic systems have several technological and biomedical applications such as environment protection, energy production, bioremediation, sensors and immunoassays design, and drug delivery devices...

The application of nanotechnological innovations to increase the effectiveness bioflavonoid quercetin is considered. ability functionalize with specific ligands that target organs or cells very important because it possible concentration at desired level while reducing side effects. Quercetin, as a flavonoid antioxidant, widely used reduce oxidative stress and activate signalling pathways in ce...

The ternary I-III-VI(2) semiconductor of CuInSe(2) nanoparticles with controllable size was synthesized via a simple solvothermal method by the reaction of elemental selenium powder and CuCl as well as InCl(3) directly in the presence of anhydrous ethylenediamine as solvent. X-ray diffraction patterns and scanning electron microscopy characterization confirmed that CuInSe(2) nanoparticles with ...

Human homeobox protein (Nanog) is highly expressed in most cancer cells and has gradually emerged as an excellent target in cancer therapy, owing to its regulation of cancer cell proliferation, metastasis and apoptosis. In this study, we prepared tumor-targeting functionalized selenium nanoparticles (RGDfC-SeNPs) to load chemotherapeutic doxorubicin (DOX) and Nanog siRNA. Herein, RGDfC peptide ...

Conventional mechanochemical synthesis of zinc selenide, ZnSe nanoparticles was performed in a planetary ball mill by highenergy milling of zinc (Zn) and selenium (Se) powders. Mechanochemically synthesized ZnSe was subsequently re-milled in circulation mill in ZnCl2 solution in order to study de-aggregation, physical-chemical and optical properties of ZnSe nanoparticles. The mechanochemically ...