The aim of this study was to evaluate the effect of organic selenium supplementation on the immune response of broilers vaccinated against coccidiosis, Infection Bursal Disease Virus (IBDV) and Newcastle Diseases Virus (NDV). The study included three treatments (T), T1= control (inclusion of inorganic selenium in a basal diet), T2= basal diet + 0.2 ppm of organic selenium as selenomethionine an...

There are no two main-group elements that exhibit more similar physical and chemical properties than sulfur and selenium. Nonetheless, Nature has deemed both essential for life and has found a way to exploit the subtle unique properties of selenium to include it in biochemistry despite its congener sulfur being 10,000 times more abundant. Selenium is more easily oxidized and it is kinetically m...

AIM To study the bioavailability of selenium enriched yeast in preterm infants living in a low selenium area (Hungary). METHODS Thirty six preterm infants were randomly assigned to two groups at birth with respect to selenium supplementation. In the supplemented group (n = 18) infants received 4.8 mg of selenium enriched yeast containing 5 micrograms selenium daily. RESULTS In the supplemen...

This study was conducted to determine the geographic distribution of selenium deficiency among beef cows and heifers in selected states. Whole blood selenium concentrations were determined for cows and heifers on 253 cow-calf operations in 18 states. Overall, 7.8% of the samples were severely deficient, and another 10.4% of the samples were considered marginally deficient for selenium. Blood se...

The effect of selenium supplementation on recurrent hyperthyroidism caused by Graves' disease is unclear. Our study aimed to assess the efficacy of selenium supplementation therapy on recurrent Graves' disease. Forty-one patients with recurrent Graves' disease were enrolled in this study. All patients received the routine treatment using methimazole (MMI), while patients allocated to the seleni...

Blood selenium and trace minerals play an important role in animal's health and production. The aims of this study were to determine selenium effect on blood glutathione peroxidase (GPX) activity, trace minerals and weight gain in lambs. Twelve female Makuei breed were studied for 63 days in groups of control, nanoselenium (NanoSe) and sodium selenite (NaSe). Mean concentrations of GPX, Cu and ...

Selenium offers important health benefits, including the prevention of some types of cancer. The traditional selenium indexes, such as selenium concentration, do not account for the metabolic status of this element regarding its chemoprotective effect. Then, the knowledge of a group of proteins that respond to selenium supplementation could be useful in the assessment of the metabolic status of...

The trace element selenium is of high importance for many of the body's regulatory and metabolic functions. Balanced selenium levels are essential, whereas dysregulation can cause harm. A rapidly increasing number of studies characterizes the wide range of selenium dependent functions in the human body and elucidates the complex and multiple physiological and pathophysiological interactions of ...

BACKGROUND The association between serum selenium levels and type 2 diabetes mellitus (T2DM) is controversial. We performed a systematic review and non-linear dose-response meta-analysis of observational studies to investigate the association in the present study. METHODS A comprehensive literature search was conducted using MEDLINE and EMBASE databases. A pooled odds ratio (OR) and related 9...

The role of the micronutrient, selenium, in human cancers associated with chronic inflammations and persistent infections is poorly understood. Peritoneal plasmacytomas (PCTs) in strain BALB/c (C), the premier experimental model of inflammation-dependent plasma cell transformation in mice, may afford an opportunity to gain additional insights into the significance of selenium in neoplastic deve...