Phage-assisted continuous evolution (PACE) uses a modified filamentous bacteriophage life cycle to substantially accelerate laboratory evolution experiments. In this work, we expand the scope and capabilities of the PACE method with two key advances that enable the evolution of biomolecules with radically altered or highly specific new activities. First, we implemented small molecule-controlled...

Background: Metabolic syndrome (MetS) is a collection of various interrelated risk factors that appear to have an impact as development of atherosclerotic cardiovascular disease (CVDs). Epidemic of childhood and adolescent’s obesity has increased interest in the metabolic syndrome (MS) due to the potential projection into adulthood. The prevalence of MS in adolescents has been estimated t...

This paper presents an extensive literature survey of the software COTS component selection methods published to date, followed by a metamodel consolidating the activities and practices of these methods. Together with data collected from practitioners and researchers in the embedded systems domain, we provide concrete recommendations which will enable organizations to identify suitable practice...

Learning Management System (LMS) development has become a high priority project for educational institutions and organizations, as it provides the virtual environment for online education. Acquiring and deploying a LMS is a difficult task that involves risks related with costs and time. The goal of this research in progress is to introduce an extension in the Rational Unified Process (RUP) in o...

Lipases are enzymes used in various industrial sectors such as food, pharmaceutical and chemical synthesis industries. The selection of microorganisms isolated from soil or wastewater is an alternative to the discovery of new species with high enzymes productivity and with different catalytic activities. In this study, the selection of lipolytic fungi was carried out by submerged fermentation. ...

This study aims to explore whether college and family social capital influences the job selection of college students. When demographic variables such as gender and college type are controlled for, logistic regression of 2,145 college students shows that only college social capital, such as peer friendship (β = .160), extracurricular activities (β = .096), and academic advisors counseling (β = ...

An essential question for every business is " How is value created? " Since the industrial age, value is created through a value chain, a chain of consecutive value activities that all together create a tangible product. However, with the current information technology, our economy shifts increasingly towards the economic offering of more complex, intangible products. Enabled by information tec...