Epilepsy is a complex disease, characterized by the repeated occurrence of bursts of electrical activity (seizures) in specific brain areas. The behavioral outcome of seizure events strongly depends on the brain regions that are affected by overactivity. Here we review the intracellular signaling pathways involved in the generation of seizures in epileptogenic areas. Pathways activated by modul...

Objective(s): While traumatic brain injury (TBI) is a predisposing factor for development of post-traumatic epilepsy (PTE), the occurrence of seizures following brain trauma can infuriate adverse consequences of brain injury. However, the effect of seizures in epileptogenesis after mild TBI cannot yet be accurately confirmed. This study was designed to investigate the ...

Around 0.6-0.8% of the world’s population is affected by a re-current neurological disorder of epilepsy. Second only to stroke, epileptic seizures interrupt lives of 50 million people. The sudden and seemingly unpredictable nature of seizures is one of the most defeating facts of epilepsy. The ability to predict a rising seizure reliably can mitigate the severity of the disorder and open up new...

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The generalized differential quadrature (GDQ) method is used to obtain the computational results of two-layer cross-ply laminated shell under rapid uniform heat induced vibration. In the thermally insulated vibration analyses of a laminated shell, the sudden uniform heat input over its lower surface only and temperature load is linear of axial coordinate. The GDQ method provides a method for ca...

Many studies have focused on the nonlinear analysis of electroencephalography (EEG) mainly for the characterization of epileptic brain states. It is assumed that at least two states of the epileptic brain are possible: the interictal state characterized by a normal apparently random, steady-state EEG ongoing activity; and the ictal state that is characterized by paroxysmal occurrence of synchro...

We report a 29-year-old man with secondarily generalised seizure and cardiac impairment. He was an indulger in betel nuts without other aetiological or precipitating factors, and no abnormality on neuroradiologic investigation. The occurrence of his seizures related to an overdose of betel nuts. It is clinically important to know that epilepsy may be induced by betel nut chewing.

Objective: To identify the incidence of seizures within 48 hours COVID-19 vaccination in PWE Methods: This is a retrospective cross-sectional observational study performed at two Northern Virginia neurology clinics. that had been vaccinated against were surveyed to report occurrence seizure and presence additional triggers surrounding seizure. Results: Of 189 patients included analysis, 13 (7%)...