نتایج جستجو برای: segmental duplications
تعداد نتایج: 25176 فیلتر نتایج به سال:
In addition to variation in terms of single nucleotide polymorphisms (SNPs), whole regions ranging from several kilobases up to a megabase in length differ in copy number among individuals. These differences are referred to as Copy Number Variants (CNVs) and extensive mapping of these is underway. Recent studies have highlighted their great prevalence in the human genome. Segmental Duplications...
A DNA sequence can be analyzed as a text of four letters by counting the times each word in the set of k-letter words occurs in the text. If the text is random and long enough, then the frequencies of word occurrence are expected to obey a Poisson distribution. Examination of complete microbial genomes shows that for k less than 9, the distribution has a width many times the width of a Poisson ...
An unexpected finding of the human genome was the large fraction of the genome organized as blocks of interspersed duplicated sequence. We provide a comparative and phylogenetic analysis of a highly duplicated region of 16p12.2, which is composed of at least four different segmental duplications spanning in excess of 160 kb. We contrast the dispersal of two different segmental duplications (LCR...
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