C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) are known as acute phase proteins, which reflect a measure of the acute-phase response. The term “acute phase” refers to local and systemic events that accompany inflammation. Local responses include vasodilation, platelet aggregation, neutrophil chemotaxis, and release of lysosomal enzymes. Systemic responses include fever, leuk...

1. Jeunemaitre X, Soubrier F, Kotelevtsev YV, Lifton RP, Williams CS, Charru A, et al. Molecular basis of human hypertension: role of angiotensinogen. Cell 1992;71:169–80. 2. Doria A, Onuma T, Gearin G, Freire BS, Warram JH, Krolewski AS. Angiotensinogen polymorphism M235T, hypertension, and nephropathy in insulin-dependent diabetes. Hypertension 1996;27:1134–9. 3. Gardemann A, Stricker J, Humm...

In a previous communication3 a simple method of estimating the sedimentation rate (S.R.) was described which had the great advantage of requiring only a finger prick. Close agreement between the degree of rheumatic activity and the height of the sedimentation rate was demonstrated. This has been confirmed by Bach and Gray Hill', Struthers and Bacal6, Perry4 and others. In this paper it is propo...

The aim of this study was to investigate the effect of spinal anesthesia on erythrocyte sedimantation rate (ESR). After approval by the local ethics committee and written informed patient consent, patients between the ages between the ages of 18-65 and American Society of Anesthesiologists (ASA) physical status classification, Class I-II scheduled for ilioinguinal and anorectal surgery under sp...

BACKGROUND C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) have been shown to be useful for diagnosis of prosthetic hip and knee infection. Little information is available on CRP and ESR in patients undergoing revision or resection of shoulder arthroplasties or spine implants. METHODS/RESULTS We analyzed preoperative CRP and ESR in 636 subjects who underwent knee (n=297), hi...

Polymyalgia rheumatica is a relatively common syndrome of the elderly characterized by severe pain and stiffness in the neck shoulder and pelvic girdles, along with increased acute phase reactants. The current diagnostic criteria include as a requirement an erythrocyte sedimentation rate (ESR) higher than 30 or 40 mm/1 hr. Nevertheless, in several reports, a sizable proportion of patients with ...

MANSY observers maintain that in the Westergren method of determining the sedimentation rate (S.R.) of red blood cells (R.B.Cs.) on a column of blood 200 mm. high, the fall at the end of the first or second hour gives all the required information. In a method affected bymany variable factors it is inadvisable to over-elaborate the technique; at the same time it is worth while to obtain the maxi...

Asbestos related lesions of the lung parenchyma and the pleura can be divided into three main types: parietal pleural plaques, diffuse interstitial fibrosis ("classical asbestosis"), and a third type of reaction affecting both the pleura and the lung parenchyma. The last type includes such lesions as acute pleurisy, diffuse pleural thickening, and rounded atelectasis. Among 1344 patients with a...

The peroxydatic activity of haemoglobin in the presence of hydrogen peroxide catalyses the oxidation of TMB to a coloured product. Haemoglobin peroxidase has been termed a 'pseudoperoxidase'7 because, unlike true peroxidases which exhibit specificity for phenols, erythrocytes contain a peroxidase (erythrocyte glutathione peroxidase) specific for oxidation of reduced glutathione. This causes the...

Dear Editor: The erythrocyte sedimentation rate (ESR) is commonly determined in laboratory blood testing and is often elevated in patients with underlying systemic disorders. In 1983, Miller et al.1 clarified the upper limits of ESR and, since then, these parameters have been widely applied in clinical practice. In a study of the upper limits of ESR based on 26 836 healthy men and 1076 nonpregn...