The traditional system of the medicine remains the major source of the health care. It is safe alternative, lesser cost and better tolerance and its complications. The major defense against free radical compounds found in medicinal plants is in the form of natural antioxidants. The present investigation is an attempt to assess the bioactivity of daily oral administration of methanolic extract o...

Thirty two apparently healthy local non descript cows were experimentally divided into two groups viz. treatment and control group having 16 animals each. The animals under treatment group were fed dried stem powder of Tinospora cordifolia (100 mg/ kg BW) by mixing it in concentrate mixture for a period of 5 days. The control group animals were fed equal amount of the basal concentrate mixture ...

OBJECTIVE To optimize the conditions for the extraction of alkaloid palmatine from Tinospora cordifolia by using response surface methodology (RSM) and study its anticancerous property against 7,12-dimethylbenz(a)anthracene (DMBA) induced skin carcinogenesis in Swiss albino mice. METHODS The effect of three independent variables, namely, extraction temperature, time, and cycles was investigat...

Pharmaceutical Manufacturing is an important enterprise and oral tablet manufacturing is the most significant of all, because more drugs are made as tablets than any other dosage form. The way of tablet manufacturing has been undergoing change in recent years and is likely to head in new directions. In this study Tinospora cordifolia (guduchi) a freely available, a climbing shrub belonging to t...

Objectives: The present study undertaken to explore antioxidant and the cell line of isolated compound from ethanol extract Tinospora cordifolia belongs family Menispermaceae.
 Methods: air dried powdered sample aerial parts T. was extracted in a Soxhlet using five different solvents. Most active extracts were purified silica gel column chromatography. Characterized structure Fourier trans...

Natural remedies from medicinal plants are considered to be effective and safe alternative treatment for diabetes mellitus. The aim of present study was to demonstrate the hypoglycemic and anti-diabetic activity of the Ethanolic extract of tinospora cardifolia whole plant in alloxan induced diabetic animals with a view to explore its use for the treatment of diabetes mellitus in humans. The Eth...

BACKGROUND & OBJECTIVES The pathogenicity of the nosocomial pathogens, Pseudomonas aeruginosa and Acinetobacter baumannii is regulated by their quorum sensing (QS) systems. The objective of the present study was to examine the effect of the cold ethyl acetate extract of Tinospora cordifolia stem on virulence and biofilm development in the wild type and clinical strains of P. aeruginosa and A. b...

Tinospora cordifolia (Guduchi or Amrita) is an important drug of Ayurvedic System of Medicine and found mention in various classical texts for the treatment of diseases such as jaundice, fever, diabetes and skin disease etc. In present times, this drug has been subjected for numerous chemicals, pharmacological, pre-clinical and clinical investigations and many new therapeutic applications have ...