Dentin hypersensitivity (DH) is a painful response to stimulus applied to the open dentinal tubules of a vital tooth. It's a common oral condition, however, without an ideal treatment available yet. This work evaluated in vitro the effect of micron-sized particles from a novel bioactive glass-ceramic (Biosilicate) in occluding open dentinal tubules. A dentin disc model was employed to observe c...

Enamel and dentin compose the crowns of human teeth. They are joined at the dentinoenamel junction (DEJ) which is a very strong and well-bonded interface unlikely to fail within healthy teeth despite the formation of multiple cracks within enamel during a lifetime of exposure to masticatory forces. These cracks commonly are arrested when reaching the DEJ. The phenomenon of crack arrest at the D...

OBJECTIVE The aim of this study was to evaluate the 5 year clinical dentin bonding effectiveness of two HEMA-free adhesives in Class V non-carious cervical lesions. MATERIAL AND METHODS A total of 169 Class V restorations were placed in 67 patients with a self-etching adhesive (G-Bond; 67), a 3-step HEMA and TEGDMA free etch-and-rinse (cfm; 51) and a control HEMA-containing etch-and-rinse adh...

introduction: the purpose of a desensitizing agent is a permanent coating or filling of dentin surface. morphological analysis in vitro of this treated surface is essential to understand the interaction between desensitizing agent and hypersensitive dentin. the aim was to evaluate the morphology of four dentin surface treated with desensitizing agents. methods: this was an in vitro laboratory s...

The aim was to state the different applications and effectiveness of polymeric zinc-doped nanoparticles achieve dentin remineralization. Literature search conducted using electronic databases, such as PubMed, MEDLINE, DIMDI, Embase, Scopus Web Science. A narrative exploratory review undertaken. Polymeric nanospheres (NPs) were efficiently loaded with zinc. NPs sequestered calcium phosphate in p...

We reported previously that Nfic-deficient mice exhibit short and abnormal molar roots and severely deformed incisors. The objective of this study is to address the mechanisms responsible for these changes using morphological, IHC, and RT-PCR analysis. Nfic-deficient mice exhibited aberrant odontoblasts and abnormal dentin formation in molar roots and the labial crown analog of incisors. The mo...

This study investigated the effect of Er:YAG laser on bonding to dentin and the interaction pattern of different adhesive systems with the lased substrate. Tensile bond strength of a self-etching [Clearfil SE Bond (CSEB)] and two total-etch [Single Bond (SB) and Gluma One Bond (GOB)] systems to lased and non-lased dentin was evaluated and the adhesive interface morphology was examined by SEM. D...

Dentin matrix protein 1 (DMP1) is an acidic phosphoprotein that plays an important role in mineralized tissue formation by initiation of nucleation and modulation of mineral phase morphology. The purpose of the present study was to examine the immunoexpression of DMP1 in tooth germs of 7 human fetuses at different gestational ages (14, 16, 19, 20, 21, 23 and 24 weeks) comparing with completed t...

Our previous studies have demonstrated that nuclear factor I-C (NFI-C) null mice developed short molar roots that contain aberrant odontoblasts and abnormal dentin formation. Based on these findings, we performed studies to elucidate the function of NFI-C in odontoblasts. Initial studies demonstrated that aberrant odontoblasts become dissociated and trapped in an osteodentin-like mineralized ti...