a 3-month-old short haired pointer with crusty local alopecia around the eyes was presented to smallanimal hospital of tehran university. scraping and biopsy were obtained from lesions of affected area.notoedres sp. was diagnosed in skin scraping by parasitologic examination. furthermore, histopathology oflesions demonstrated moderate hyperplastic epidermis, parakeratosis and acanthosis.

Glioblastoma multiforme (GBM) is one of the most therapeutically refractory human cancers. Elevated cellular polyamine levels are a common feature of cancer cells, including GBM cells, and the polyamine pathway has been explored as a potential therapeutic target to inhibit polyamine biosynthesis or activate polyamine catabolism. In this study, we investigated the effect of N1,N11-diethyl-norspe...

PURPOSE Analogues of the naturally occurring polyamines, alkylated on both terminal amines, are being developed as anticancer drugs. Because bisalkylated derivatives of putrescine (1,4-diaminobutane) are potent inhibitors of the flavin adenine dinucleotide-dependent polyamine oxidase (PAO), we asked whether PAO could detoxify synthetic bisalkylated polyamines with chain lengths longer than putr...

  Various parasite species were found in Carassius carassius including Diplostomum spathaceum, Dactylogyrus sp.,Gyrodactylus sp. Ichthyophthirius multifiliis and Trichodinia sp . They were found in four rivers in West Azerbaijan Province (North-Western Iran) . A total of 207 live Carassius carassius from four rivers including Aras (72) Zariyneh (42) Nazlo (58) and Barandoz (35) were studied. Pa...

screening and identification of moderately halophilic protease producing bacteria from different regions of maharloo, a hypersaline lake in the southern area of iran, were the objectives of this study. in the preliminary screening, 16 isolates exhibited proteolytic activity on saline skim milk agar. all isolates were able to grow comfortably in the media containing 7-15% of salt. protease activ...

contamination of human and animal body tissues with flies’ larvae and diptera cause myiasis. a 26 yr old female patient refers to kashan shahid beheshti hospital, central iran because of urogenital infection, pain in the right part of stomach, smelly and reddish vaginal discharge and frequent urination. in the first checking, urine sample was taken. in the sample, active and alive larvae were s...

Abstract Background Medical treatment (MT) is key in the management of Inflammatory Bowel Disease (IBD, ulcerative colitis [UC] and Crohn’s disease [CD]) non-adherence a barrier to efficacy. Approximately 30 % patients with IBD non-adherent MT. Self-care defined as; process maintaining health through health-promoting practices managing illness. Adherence an important part self-care IBD. Illness...