It is known that feature selection/screening for high-dimensional nonparametric models an important but very difficult issue. In this paper, we first point out the limitations of existing screening methods. particular, model-free sure independence methods, which are defined on random predictors, may completely miss some features in underlying function when predictors follow certain distribution...

Since the mid-1990s, the Israeli medical scene has witnessed a real boom in elective prenatal testing for inherited diseases that has spread beyond risk groups to the general Jewish population, especially of Ashkenazi (European) origin. This study tried to identify key social influences involved in the growing range and prevalence of prenatal genetic tests as they emerged from women's own persp...

background: computerized preventive screening software is a cost effective intervention tool to address non-communicable chronic diseases. shiraz smart screening software (ssss) was developed as an innovative tool for qualified screening. it allows simultaneous smart screening of several high-burden chronic diseases and supports reminder notification functionality. the extent in which ssss affe...

During the past decade we have seen dramatic advances in colon cancer screening. Reduction in mortality in average risk screening for colorectal cancer has now been shown in multiple trials. Efforts to increase public awareness and compliance with evidence-based screening guidelines are underway. Recent guidelines have incorporated family history, as it has been identified as a common risk fact...

Genetic epidemiology is a rapidly expanding research field, but the implications of findings from such studies for individual or population health are unclear. The use of molecular genetic screening currently has some legitimacy in certain monogenic conditions, but no established value with respect to common complex diseases. Personalised medical care based on molecular genetic testing is also ...

In Europe a process of harmonisation of standards and regulations on genetic testing has started. Public discussion and consultation are recommended, but it is not clear in every European country how the decision making process as regards the further introduction of genetic testing services should be formed. In this paper the usefulness and importance of an overseeing body for genetic screening...