BACKGROUND Onchocerciasis results from infestation by the nematode Onchocerca volvulus, and is characterized clinically by troublesome itching, skin lesions and eye manifestations. Since 1992, approximately 9,000 immigrants have arrived in Israel from the Kuwara province of northwest Ethiopia where the prevalence of onchocerciasis is particularly high. OBJECTIVES To determine whether onchocer...

Finally, familial cutaneous collagenoma must be differentiated from two distinct types of eruptive collagenoma. Eruptive collagenoma type 1 is clinically and histologically similar to familial cutaneous collagenoma but without documented familial inheritance. Eruptive collagenoma type 2 presents cutaneous lesions smaller than those of familial cutaneous collagenoma and arranged on the extremiti...

BACKGROUND Reticular erythematous mucinosis (REM syndrome) is a rare cutaneous disease that predominantly affects the chest and upper back area of middle-aged women. Although antimalarial treatment is generally considered the most effective approach, only a few case reports exist on its use in REM syndrome. OBSERVATIONS A total of 11 patients with REM syndrome (10 women and 1 man), mean age, ...

BACKGROUND Reticular erythematous mucinosis (REM) syndrome is a rare disorder. Its clinical course is cyclic with remissions and exacerbations. In this disease, photosensitivity has previously been noticed but rarely demonstrated. We report three new cases with positive photobiological investigation. CASE REPORTS Three patients (two males, one female) with a mean age 47 years were seen with r...

Those who support the connective tissue origin will further dividemucinousnevi into 2histopathologic types: a connective tissuenevusof theproteoglycan (CTNP) typeandcombinedepidermal-CTNPtype.1 InCTNP, theepidermis isnormal, while in epidermal-CTNP, the epidermis shows hyperkeratosis and acanthosis with elongation of the rete ridges consistentwithanepidermalnevus.1Regardlessof classification, t...

Background: Lichen Planus (LP) is a unique, common inflammatory disorder that affects the skin, mucous membrane, nail and hair. Though lichen planus has distinct colour, morphology and distribution it can present with variability. Objective: To know the incidence, various clinical manifestations, and correlation with histopathological findings. Methods: A total of 50 Lichen planus patients atte...

An 80-year-old Caucasian female patient presented with a two-year history of intensively itching skin rash located on her left lower leg and mild swelling of the proximal interphalangeal and metacarpophalangeal joints, accompanied by morning stiffness around these joints, lasting at least one hour before maximal improvement (Figures 1A and 1B). She reported having had a long-lasting medical his...

This is an ambitious undertaking, as suggested by the lengthy title, and the authors successfully cover endocrine, metabolic, nutritional, and deposition disorders. The book is all the more thorough as there is seamless assimilation of clinical, histologic, and radiologic information for these diseases. The aims are fulfilled with 1) concise text, 2) atlas-like inclusion of over 174 clinical ph...

A 70-year-old white woman presented a papular zosteriform eruption on her right upper thorax and right arm. Shiny, erythematous-purplish or £esh-coloured papules 2 ^ 3 mm in diameter were observed, isolated or closely arranged in little plaques (Fig. 1). The patient complained only of mild itching; no systemic signs and symptoms were referred. Two months earlier the patient had a C5 ^ C6 right ...

Whether or not these are simply different stages of the same disease process is unknown, but certainly rheumatoid subjects not uncommonly show more than one type of lesion during the later stages of the disease. The most readily recognized clinical manifestations of rheumatoid vascular disease are those involving the skin. Crops of nail-edge lesions and petechia-like lesions of the finger pulps...