background: oyan reservoir, south-west nigeria was constructed in 1984 to generate electricity but has altered the exist­ing physical, biological and socio-economic environment of the people. this study, carried out between october 2006 and march 2008, aimed at investigating the current status of schistosoma haematobium infection around the reservoir. methods: urine samples from 536 participant...

background: the study was conducted to estimate and compare the validity and performance of two screening methods for uri­nary schistosomiasis: the interview - reporting blood in urine- and detecting microhematuria by reagent strip. methods:  in year 2003, 515 schoolchildren from five schools in abyan and taiz governorates in yemen, were in-terviewed by healtworker for hematuria, and then urine...

INTRODUCTION Schistosomiasis (bilharzia), one of the most relevant parasitoses of humans, is confirmed by microscopic detection of eggs in stool, urine, or organ biopsies. The sensitivity of these procedures is variable due to fluctuation of egg shedding. Serological tests on the other hand do not distinguish between active and past disease. In patients with acute disease (Katayama syndrome), b...

BACKGROUND Mass drug administration (MDA) of praziquantel has been the intervention of choice against schistosomiasis but with limited success in interrupting the transmission. The development of anti-Schistosoma vaccines is underway. Our objective is to quantify the population-level impact of anti-Schistosoma vaccines when administered alone and in combination with mass drug administration (MD...

increased number of mast cells at the site of infection is widely regarded as important host defense against parasites. the kinetics of mucosal mast cells and connective tissue mast cells responses were studied in the intestines of 68 female cflp mice infected with 100 schistosoma mansoni cercariae. the number of mucosal mast cells and the connective tissue mast cells increased from week 3 and ...

Praziquantel (PZQ) is an effective chemotherapy for schistosomiasis mansoni and a mainstay for its control and potential elimination. However, it does not prevent against reinfection, which can occur rapidly in areas with active transmission. A guide to ranking the risk factors for Schistosoma mansoni reinfection would greatly contribute to prioritizing resources and focusing prevention and con...

The progress of the integrated control policy for schistosomiasis implemented since 2005 in China, which is aiming at reducing the roles of bovines and humans as infection sources, may be challenged by persistent presence of infected snails in lake and marshland areas. Based on annual parasitologic data for schistosomiasis during 2004-2011 in Xingzi County, a spatio-temporal kriging model was u...

Schistosomes, a class of parasitic trematode worms, cause schistosomiasis. Accumulating evidence suggests that microRNAs (miRNAs)-small, non-coding RNAs that are known to play critical regulatory roles in many organisms-may be involved in schistosome development and sexual maturation, as well as the pathogenesis of schistosomiasis. Schistosoma miRNAs, such as Bantam and miR-10, may be involved ...

Effective interruption of the Schistosoma life cycle is essential to blocking the parasite’s transmission, and thus truly preventing human schistosomiasis over the long term. Our current mass treatment campaigns were expected to limit transmission by reducing environmental contamination with parasite eggs. However, the process of transmission has proven to be very focal and highly efficient, su...

Abstract Background Global elimination of schistosomiasis as a public health problem is set target in the new World Health Organization’s Neglected Tropical Diseases Roadmap for 2030. Due to long history interventions, Zanzibar islands Tanzania have reached this goal since 2017. However, challenges occur on last mile towards interruption transmission. Our study will investigate tools and strate...