TO THE EDITOR: Genetic factors have been suggested to play an important role in the development of achalasia, and various candidate genes have been documented. ALADIN is one of the candidate genes. However, the study by Di Nardo et al has shown that no pathogenic mutations were detected in the ALADIN gene of 41 patients with isolated achalasia. In addition, Allgrove syndrome is a rare disorder,...

Schirmer Engineering Corporation (Schirmer Engineering) was retained by The Fire Protection Research Foundation (FPRF) as a Project Consultant for the project titled “Data Needs for NFPA Automatic Sprinkler Committees.” This report investigates the NFPA 13, Standard for the Installation of Sprinkler Systems (2007 Edition) requirements for dry pipe systems having a maximum volume of 500 gallons ...

Objective: to evaluate in the ocular surface of patients postoperative period a Post-Anesthetic Recovery Unit clinical predictors for dryness nursing diagnosis (ND) Risk dryness. Method: cross-sectional study carried out from May August 2017. Sample consisted 157 patients. Data were analyzed using descriptive and inferential statistics. Results: prevailed 85.35% patients, while ND was present 1...

Aim: Today, antidepressants, which are frequently prescribed by physicians for different purposes, have various effects on ocular tissues. The aim of this study is to evaluate the agents cornea and surface. 
 Material-Methods: For purpose, 50 healthy controls 336 patients were included in study. Results: Compared control group, all patient groups had higher OSDI scores staining scores, a l...

The aim of this stu dy was to de ter mi ne the nor mal va lu es for the Schir mer tear test (STT) in Tur kish Hun ting Dogs. This was per for med in or der to fa ci li ta te the di ag no sis of xer ophthal mia or ke ra to con junc ti vi tis sic ca (KCS), which is cha rac te ri zed by de fi cien cies in tear pro duc ti on and the re sul ting ab nor mal STT. Fif teen Tur kish Hun ting Dogs (8 fe ...

PURPOSE To analyze the difference between measurements of Schirmer test I (STI) and basal Schirmer test (STB) with open and closed eyes. METHODS Sixty eyes of 30 normal volunteers, 12 males and 18 females aged 28 +/- 9 years were recruited for the study. All ST were carried out in a closed environment with the absence of airflow (humidity 60 +/- 2.34% and temperature 20.72 +/- 1.52 degrees C)...

Purpose Pharmacological activation of ocular surface cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels is a potential pro-secretory approach to treat dry eye disorders. We previously reported the discovery of aminophenyl-1,3,5-triazines, one of which, N-methyl-N-phenyl-6-(2,2,3,3-tetrafluoropropoxy)-1,3,5-triazine-2,4-diamine (herein called CFTRact-K267), fully activa...

The effect of hydroxychloroquine (HCQ) on dry eye has not been fully determined. This study aimed to compare the 12-week efficacy of HCQ medication with that of a placebo in the management of dry eye in primary Sjögren's syndrome (pSS). A double-blind, randomized control study was conducted in 39 pSS subjects from May 2011 through August 2013. pSS was diagnosed based on the classification crite...

PURPOSE To analyze the influence of botulinum toxin on the lacrimal function of patients with facial dystonias. METHODS Patients with the diagnosis of hemifacial spasm or benign essential blepharospasm were evaluated and invited to answer the Ocular Surface Index Disease (OSID) questionnaire. All patients underwent Schirmer I and basal tests; break-up time (BUT) test and lacrimal clearance ev...