[1] I show that the latest series of climate models reproduce the observed mid-depth Southern Ocean warming since the 1950s if they include time-varying changes in anthropogenic greenhouse gases, sulphate aerosols and volcanic aerosols in the Earth’s atmosphere. The remarkable agreement between observations and state-of-the art climate models suggests significant human influence on Southern Oce...

An extension of the infomax algorithm of Bell & Sejnowski (1995) is presented that is able to separate the mixed suband super-Gaussian source distributions. The same learning rule has been derived by Giiolami & Fyfe (1997) from the negentropy perspective for projection pursuit. Using a Laplacian prior we also propose a learning rule that is especially convenient to realize in hardware. The natu...

The protein binding of non-steroidal anti-inflammatory drugs flurbiprofen, ketoprofen and etodolac with human serum albumin (HSA) was investigated using indirect chiral high performance liquid chromatography (HPLC) and ultrafiltration techniques. S-(-)-1-(1-naphthyl)-ethylamine (S-NEA) was utilized as chiral derivatization reagent and pre-column derivatization RP-HPLC method was established for...

UNLABELLED Multidimensional Treatment Foster Care (MTFC) has been shown to be an evidence based alternative to residential rearing and an effective method to improve behavior and attachment of foster children in the US. This preliminary study investigated an application of MTFC for preschoolers (MTFC-P) in the Netherlands focusing on behavioral outcomes in course of the intervention. To examine...

Carbon-11-YM-09151-2 binds highly selectively to D2 dopamine receptors in the brain. Using this ligand, D2 dopamine receptor density (Bmax) and affinity (Kd) in canine striatum were measured. After administering various doses of the ligand in nine experiments, regional uptake was followed by repeated PET scanning for up to 80 min. D2 dopamine receptor specific binding at equilibrium was defined...

PURPOSE To provide the first detailed information about native language abilities of children who are or had been institutionalized. METHOD The language of ten 30-month-old children raised in Romanian orphanages was compared with that of 30 chronological-age-matched peers: 10 children who had moved recently from orphanages to foster care, 10 children in foster families for at least 1 year, an...

Two classes of receptors for 125I-labeled nerve growth factor in chick embryonic dorsal root neurons have been observed. One type is associated with the plasma membrane (or microsomal fraction) and can be completely solubilized by Triton X-100. These receptors display the nonsaturable binding isotherms and curvilinear Scatchard plots previously reported for nerve growth factor receptors in whol...

Molecularly imprinted polymers (MIP’s) for quercetin were successfully synthesized by a thermal polymerization method using quercetin as template molecule, acrylamide as functional monomer and ethylene glycol dimethacrylate as cross-linker in the presence of four different porogenic solvents: 1,4-dioxane, tetrahydrofuran (THF), acetone, and acetonitrile. The selective performance of obtained MI...