There is a widening gap between basic research and clinical practice, particularly for colorectal cancer. In recent years, many have expressed concerns regarding the disconnection between the promises of basic science and the delivery of better individual health. In this paper we describe some of our research in serum proteomics, microarrays and minimal residual disease dedicated to this field ...

As Leifer et al. have argued, the management of radical innovation projects necessitates different strategies and practices, including different ways of measuring performance. This paper discusses our efforts to explore indicators of progress for radical innovation in basic and applied research and technology development at both the project and programme levels. The paper provides examples of o...

Librarians are being urged to conduct research as one of their professional responsibilities. Many librarians, however, avoid research, because they believe it is beyond their capabilities or resources. This paper discusses the importance of conducting applied research-research directed toward solving practical problems. The paper describes how one library conducted practical research projects,...

The main objective of this research is to design and operate a prediction market inside an R&D community, to assess the emergence and the evolution of mobile technologies. To support this research, we iteratively developed and evaluated several prototypes. We intend to demonstrate the successful use of prediction markets for predicting the impact of a research activity. Furthermore, following a...

In order to enhance biomedical research and development efficiency and innovation, nontraditional research collaborations have emerged that feature the sharing of information, resources, and capabilities. Although many of these so-called precompetitive collaborations are in the field of oncology, the lessons they offer are broadly applicable to other subfields of translational medicine.

BACKGROUND Community-based participatory research (CBPR) approaches that involve community and academic partners in activities ranging from protocol design through dissemination of study findings can increase recruitment of medically underserved and underrepresented racial/ethnic minority populations into biomedical research. METHODS Five cancer screening and prevention trials in three Nation...

Public administration scholars often associate increased public participation in policy implementation with the advancement of democratic values. Likewise, scholars engaged in the various forms of action research (AR) promote their efforts as a means to democratizing the research process or contributing to improved social outcomes. Despite these common interests in participation and democracy, ...

Traditionally, biomedical research has been carried out mainly within departmental boundaries. However, successful biomedical research increasingly relies on development of methods and concepts crossing these boundaries, requiring expertise in different disciplines. Recently, major research institutes have begun experimenting with ways to foster an interdisciplinary ethos. The Evans Center for ...

Over the last three decades a large number of Operations Research (OR) studies in the context of developing nations have been published. Many of these studies deal with public policy issues. Using OR case studies in the context of Bangladesh health and agriculture sectors, this study investigates the development process of these models and identifies the challenges for implementing the results ...

There are several reasons why qualitative research is a suitable means to answer a number of relevant nursing research issues. However, as a research methodology it is not without its critics. This article debates the importance of qualitative research to nursing knowledge and uses the literature and practice experience to evaluate its contribution.