UNLABELLED An increased risk among siblings of probands with complex regional pain syndrome (CRPS) may be indicative of a genetic contribution. We calculated the sibling recurrence risk ratio (lambda(sibling)), a measure of familial aggregation. We surveyed 405 CRPS patients to collect information on the occurrence of CRPS in their siblings and compared this risk with the population risk to dev...

Few studies include siblings’ experiences with anorexia nervosa (AN). Aims: Describe patients’ and retrospective views on how AN influenced their life in the acute phase of illness at 4.5-years follow-up. Method: 34 former patients 13 siblings that had participated family-based inpatient treatment for completed questionnaires Results: Patients reported high, moderate, levels negative influences...

The role of sibling relationship lasts for a life-time as the siblings spend more time with each other than with their parents. The sibling bond is a special one. This paper addresses the initial results from the pilot study (AprilMay, 2016) of the research on siblings of children with disabilities. Twelve face-to-face interviews were conducted with siblings without disabilities in the age grou...

BACKGROUND Enzyme replacement therapy (ERT) with laronidase, (recombinant human α-L-iduronidase; Aldurazyme) is the primary treatment option for patients with attenuated mucopolysaccharidosis type I (MPS I). This study examined the effect of early ERT on clinical manifestations. METHODS This multinational, retrospective case series abstracted data from records of 20 patients with Hurler-Schei...

An adoption study of genetic effects on obesity in adulthood was carried out in which adoptees separated from their natural parents very early in life were compared with their biological full and half siblings reared by their natural parents. The adoptees represented four groups who by sampling from a larger population were categorised as either thin, medium weight, overweight, or obese. Weight...

In many families, siblings play important roles in shaping each other's outcomes and experiences across development. In adoptive families, siblings may affect adoptees' feelings about adoption and birth family contact. Among "target adoptees" (i.e., 1 participating adopted individual within adoptive families) with siblings who may have also been adopted or the biological children of the adoptiv...

Non-verbal referential communication is impaired in children with Autism Spectrum Disorders (ASD). However, the development of difficulties with referential communication in the younger siblings of children with ASD (High-Risk Siblings)-and the degree to which early referential communication predicts later autism symptomatology-is not clear. We modeled the early developmental trajectories of th...

We used transcranial magnetic stimulation to investigate whether the cortical excitability changes observed amongst the different generalized and focal epilepsy syndromes are reflected in their asymptomatic siblings and if these changes depended on the clinical phenotype. We studied 157 patients with epilepsy (95 generalized and 62 focal) and their asymptomatic siblings (138 and 82, respectivel...

This descriptive, exploratory study investigated the social support interventions received by school-aged siblings of children with cancer and which of those interventions are perceived as being helpful. A comparison between the siblings' and parents' perceptions was made. The conceptual framework was guided by House's (1981) work on social support, which includes major categories of support va...

Recent empirical work has demonstrated the importance both of educational peer effects and of various factors that affect college choices. We connect these literatures by highlighting a previously unstudied determinant of college choice, namely the college choice made by one’s older sibling. Data on 1.6 million sibling pairs of SAT-takers reveals that younger and older siblings’ choices are ver...