Background & Aim: Onosma stenosiphon has been used as herbal medicine for healing skin cuts and rashes. However, burn healing effect of this herb has not been yet reported in pharmaceutical texts. The aim of this study was to find out the effect of herb ointment on burn healing the superficial wounds post type II burns of back and testis region in Wistar rats. Experimental: A total of...

Clobetasone butyrate is a new corticosteroid, selected for study because of its combination of good activity in the vasoconstriction test and low systemic activity in animals. Formulated as an 0.05% ointment and cream (Molivate) it was clinically effective in patients with eczema, its activity being significantly greater than that of hydrocortisone 1% or fluocortolone 0.2% (Ultradil). Under con...

A 56-year-old Japanese man hospitalized for schizophrenia and depression developed pressure ulcer on his greater trochanter due to a long-term bed rest. In spite of applying 0.003% alprostadil alfadex ointment for two months, the ulcer was not improved. Because there was some purulent discharge, we examined semi-quantitative swab bacterial culture from the ulcer and subsequently detected quadra...

to determine whether the medical treatment of anal fissure can be an effective alternative for surgery methods: retrospectively, we randomly selected 190 patients being treated for anal fissure between the years 2005-2010 in 3 equal groups: group a: patients who received medical treatment with topical nitroglycerin, group b: patient treated with topical diltiazem, and group c: patients underwen...

The most commonly used topical pharmacologic agents for symptomatic management of hemorrhoids include vasoconstrictors, astringents, anesthetics, keratolytics, corticosteroids, and antipruritic agents. Some of these drugs have been involved in contact dermatitis [1-7]. A 57-year-old woman presented with a pruritic, sharply demarcated, erythematous rash on the anogenital area that spread within ...

Topical foscarnet (PFA) and acyclovir (ACV) were compared in the dorsal cutaneous guinea pig model of herpes simplex virus type 1 infection. The relative order of efficacy was PFA cream greater than ACV cream greater than ACV ointment. In vitro studies demonstrated that PFA and ACV formulated in cream vehicles penetrated through guinea pig skin 7- to 10-fold faster than did ACV in ointment.