Greater sage-grouse (Centrocercus urophasianus) have been declining both spatially and numerically throughout their range because of anthropogenic disturbance and loss and fragmentation of sagebrush (Artemisia spp.) habitats. Understanding how sage-grouse respond to these habitat alterations and disturbances, particularly the types of disturbances and extent at which they respond, is critical t...

We present a powerful application of ultra high-throughput sequencing, SAGE-Seq, for the accurate quantification of normal and neoplastic mammary epithelial cell transcriptomes. We develop data analysis pipelines that allow the mapping of sense and antisense strands of mitochondrial and RefSeq genes, the normalization between libraries, and the identification of differentially expressed genes. ...

An essential step in Serial Analysis of Gene Expression (SAGE) is tag mapping, which refers to the unambiguous determination of the gene represented by a SAGE tag. Current resources for tag mapping are incomplete, and thus do not allow assessment of the efficacy of SAGE in transcript identification. A method of tag mapping is described here and applied to the Drosophila melanogaster and Caenorh...

allelopathic plants, because of reduction in herbicide uses, are important in weed management. the allelopathic effects of sage salvia officinalis and white wormwood artemisia sieberi water extract were evaluated on germination and seedling growth of redroot pigweed amaranthus retroflexus at concentration of 0, 5, 10, 15, and 20% in controlled conditions. anova revealed that the extract concent...

We envision situation-rooms and research laboratories in which all the walls are made from seamless ultra-high-resolution displays fed by data streamed over ultra-high-speed networks from distantly located visualization, storage servers, and high definition video cameras [1,6]. It will allow local and distributed groups of researchers to work together on large amounts of distributed heterogeneo...

BACKGROUND SAGE (serial analysis of gene expression) is a powerful method of analyzing gene expression for the entire transcriptome. There are currently many well-developed SAGE tools. However, the cross-comparison of different tissues is seldom addressed, thus limiting the identification of common- and tissue-specific tumor markers. METHODOLOGY/PRINCIPAL FINDINGS To improve the SAGE mining m...

Since the introduction of serial analysis of gene expression (SAGE) as a method to quantitatively analyze the differential expression of genes, several statistical tests have been published for the pairwise comparison of SAGE libraries. Testing the difference between the number of specific tags found in two SAGE libraries is hampered by the fact that each SAGE library is only one measurement: t...

he Solvent Alternatives GuidE, better known as SAGE, has T been a joint development effort between the Research Triangle Institute and the U.S. Environmental Protection Agency since the guide’s inception in 1992. The SAGE software tool was first released in 1993 and became an immediate success for the identification and selection of alternative nonand low-polluting surface cleaning options. The...