To inquire about the possibility of durable valorization saffron, this review highlights different techniques in vitro culture and varietal creation specie. Then, a reveal main component saffron with some pharmacological activities that make product serious therapeutic hope. Saffron (Crocus sativus L.) is sterile triploid geophyte propagated by corms. respond to increasing global demand for it ...

BACKGROUND In the last two decades, pioneering research on anti-tumour activity of saffron has shed light on the role of crocetin, picrocrocin and safranal, as broad spectrum anti-neoplastic agents. However, the exact mechanisms have yet to be elucidated. Identification and characterization of the targets of bioactive constituents will play an imperative role in demystifying the complex anti-ne...

A new molecularly imprinted polymer for extraction of crocin from saffron stigmas was prepared using gentiobiose (a glycoside moiety in crocin structure) as a template. Crocin binding to gentiobiose imprinted polymer (Gent-MIP) was studied in comparison with a blank nonimprinted polymer in aqueous media. Affinity of the Gent-MIP for the crocin was more than the nonimprinted polymer at all conce...

(1) Background: Reactive oxygen species (ROS) play a crucial role in the preparation of normal wound healing response. Therefore, correct balance between low or high levels ROS is essential. Antioxidant dressings that regulate this are target for new therapies. The purpose review to identify compounds with antioxidant properties have been tested and summarize available evidence on their effects...

traditional knowledge can be used as a source for development of new medicines. in the present study, we compare the data on saffron in razi's al-hawi book with modern scientific studies. a computerized search of published articles was performed using medline, scopus as well as native references. the search terms used were saffron, crocus sativus, crocetin, crocin, safranal, razi, and al-h...

Saffron or Crocus sativus L. (C. sativus) has been widely used as a medicinal plant to promote human health, especially in Asia. The main components of saffron are crocin, picrocrocin and safranal. The median lethal doses (LD50) of C. sativus are 200 mg/ml and 20.7 g/kg in vitro and in animal studies, respectively. Saffron has been suggested to be effective in the treatment of a wide range of d...

Implication for health policy makers/practice/research/medical education: This article aims to introduce saffron as a useful herbal medicine. Copyright © 2014, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences; Published by DOCS. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution...