OBJECTIVES We have investigated the effect of a saffron supplement, given at a dose of 100 mg/kg, on prooxidant-antioxidant balance (PAB) in individuals with metabolic syndrome. MATERIALS AND METHODS A randomized, placebo-controlled trial design was used in 75 subjects with metabolic syndrome who were randomly allocated to one of two study groups: (1) the case group received 100mg/kg saffron ...

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BACKGROUND Saffron extract, a natural product, has been shown to induce apoptosis in several tumor cell lines. Nevertheless, the p53-dependency of saffron's mechanism of action in colon cancer remains unexplored. MATERIAL AND METHODS In order to examine saffron's anti-proliferative and pro-apoptotic effects in colorectal cancer cells, we treated two p53 isogenic HCT116 cell lines (HCT wildtyp...

introduction saffron as a winter active plant with low water requirement is the most strategic medicinal plant in arid and semi-arid parts of iran. this slow-growing plant has narrow leaves and no aerial stem, hence weeds can be overcome it. moreover, because of its root and canopy structure an important part of different resources is not used by this low input crop. therefore, the use of assoc...

Aim of study: Comparison saffron flowering between open field and controlled environment. Possibility transplanting.Area University Birjand (Iran)Material methods: In a first experiment, yield quality produced by traditional production system (TPS) soilless one (SPS) were compared. second the effects method, direct planting (DP) or transplanting plant (TP) in studied.Main results: Percentage co...

An NMR analytical protocol is proposed to characterize saffron samples of different geographical origin (Greece, Spain, Hungary, Turkey and Italy). A microwave-assisted extraction procedure was developed to obtain a comparable recovery of metabolites with respect to the ISO specifications, reducing the solvent volume and the extraction time needed. Metabolite profiles of geographically differen...

Saffron production will be increased in arid regions by providing sufficient water through appropriate agronomic strategies. Therefore, in this investigation the impact of different rates of super absorbent polymer (SAP) including 0,10, 20, 30, 40 and 50 kg ha-1 was studied on saffron flowering traits during two growth cycles. Results showed that the influence of experimental factor was signifi...

this research was conducted during 2009 at a regional scale in birjand and qaen counties, southern khorasan, as an attempt to develop a sustainability index (si) for quantifying the sustainability of saffron agroecosystem. the information of these agroecosystems, including socio-economic, agronomic and ecological indicators was collected using questionnaires and was subjected to statistical ana...

Tissue culture is useful method for large scale production of healthy corms and also avenues for creating variability through in vitro use of mutagens and polyploidizing agents. Induction of callus and subsequent regeneration of plants is suggested as possible means of introducing new variation. In vitro micropopagation for product formation its utility is increasing the amount of crocin, picro...