BACKGROUND The Assessment of SpondyloArthritis international Society (ASAS) definition of a positive family history (PFH) of spondyloarthritis (SpA) includes the following diseases in first- or second-degree relatives: ankylosing spondylitis (AS), acute anterior uveitis (AAU), reactive arthritis (ReA), inflammatory bowel disease (IBD), and psoriasis. However, it is not known if a PFH for each o...

Introduction Ankylosing spondylitis (AS), also known as Pierre-Marie Strumpell’s disease and, more commonly, as Bechterew’s disease, is nowadays a well-recognized inflammatory disease entity with a prevalence about 0.5%. AS primarily involves the sacroiliac joints (SIJ) and the spine, but also peripheral joints and entheses. The SIJ and spinal involvement cause chronic inflammatory back pain an...

The case is reported of a 50 year old man with longstanding seronegative rheumatoid arthritis who developed ulcerative colitis. The patient also had sacroiliitis and his tissue was typed as HLA-A2-B27 several years before the bowel disease began. A possible overlap between primary inflammatory bowel disease, complications to the treatment of rheumatoid arthritis with drugs, and gastrointestinal...