Clostridium difficile-associated disease (CDAD) is a problem of especially the frail elderly. Changes in virulence of prevalent strains in the early years of the new century saw mortality and morbidity increase from historical levels. This article explores non-antibiotic strategies including the use of probiotics. A number of avenues of ongoing research appear to have potential future clinical ...

Probiotics, because of their role in the maintenance of normal gastrointestinal flora, can facilitate human resistance to opportunistic infection and positively impact the outcome in a variety of clinical situations. Probiotics have been used successfully to facilitate treatment of bacterial vaginosis, recurrent urinary tract infections, diarrhea, bladder cancer, complications of antibiotic the...

Intestinal amebiasis has a worldwide distribution and is common in tropical and subtropical areas. [n this prospective 7-month study, we studied the main clinical findings in patients with acute amebic proctocolitis and the efficacy of Saccharomyces boulardii (SB) treatment of these patients.Initially, 57 cases with acute amebic proctocolitis were selected. The maximum occurrence of infecti...