Programmable Logic Controllers (PLCs) are the point of interaction between cyber and physical world, thus have been target previous cyber-attacks that caused disruption. To understand effectiveness state-of-the-art security mechanisms built into these devices, this paper presents an in-depth analysis performed on Siemens PLC environment, particularly communication protocol known as S7CommPlus. ...

Accumulating evidence shows the 26S proteasome is involved in the regulation of gene expression. We and others have demonstrated that proteasome components bind to sites of gene transcription, regulate covalent modifications to histones, and are involved in the assembly of activator complexes in mammalian cells. The mechanisms by which the proteasome influences transcription remain unclear, alt...

BACKGROUND The iatrogenic, HIV-related lipodystrophy is associated with development of the significant metabolic and cardiovascular complications. The underlying mechanisms of antiretroviral (ARV) drugs are not completely explored. METHODS The aim of the study was to characterize effects of the protease inhibitor (PI)--saquinavir (SQV) on metabolic functions, and gene expression during differ...

The ribosome is an evolutionarily conserved organelle essential for cellular function. Ribosome construction requires assembly of approximately 80 different ribosomal proteins (RPs) and four different species of rRNA. As RPs co-assemble into one multi-subunit complex, mutation of the genes that encode RPs might be expected to give rise to phenocopies, in which the same phenotype is associated w...

The relative accessibility of rat liver ribosomal proteins to reductive methylation was examined using ribosomes with unphosphorylated, and extensively phosphorylated S6. Comparison of the results indicated that proteins S3, S4, S7, and S23/24 of the small subunit, and proteins L9, L10, L12, L18, L27, L34, and L36 are involved in a ribosomal conformational change.

We report the draft genome sequence of the Acidovorax caeni type strain R-24608 that was isolated from activated sludge of an aerobic-anaerobic wastewater treatment plant. The closest strain to Acidovorax caeni strain R-24608 is Acidovorax sp. strain MR-S7 with a 55.4% (amino-acid sequence) open reading frames (ORFs) average similarity.

We give a description of supermembranes in nontrivial target-space geometries. A special class are the AdS4 ×S7 and AdS7 ×S4 spaces that have the maximal number of 32 supersymmetries. Lecture presented at the 22-nd Johns Hopkins Workshop, Novelties in String Theory, Göteborg, August 20-22, 1998.

We classify septic number fields which are unramified outside of {∞, 2, 3} by a targeted Hunter search; there are exactly 10 such fields, all with Galois group S7. We also describe separate computations which strongly suggest that none of these fields come from specializing septic genus zero three-