MicroRNAs (miRNAs) may be important mediators of the profound molecular and cellular changes that occur after traumatic brain injury (TBI). However, the changes and possible roles of miRNAs induced by voluntary exercise prior to TBI are still not known. In this report, the microarray method was used to demonstrate alterations in miRNA expression levels in the cerebral cortex of TBI mice that we...

Inverse Artificial neural network (iANN) is applied to optimize the parameters for hydraulic turbine runner blades. This proposed method (iANN) inverts the artificial neural network (ANN) and uses an optimization method to find the optimum parameter value (or unknown parameter) for given required conditions. In order to do so, first an ANN, which consists of a feedforward network with one hidde...

We study a generalisation of sabotage games, a model of dynamic network games introduced by van Benthem [16]. The original definition of the game is inherently finite and therefore does not allow one to model infinite processes. We propose an extension of the sabotage games in which the first player (Runner) traverses an arena with dynamic weights determined by the second player (Saboteur). In ...

A female 10,000 metre runner, aged 28, presented with a 10 day history of pain of insidious onset in the right buttock. She had, 2 weeks before presenting, competed in a track race for selection to an international representative team, which she achieved. Five days after the race she had a 400 metre interval training session, following which she was conscious of the pain in the right buttock. S...

Sacral stress fractures are uncommon injuries that are associated with repetitive load-bearing activities. The authors describe a 23-year-old male cross-country runner who presented with low back and buttocks pain. Radiographic findings were unremarkable, but a hop test identified a sacral stress fracture. The patient was instructed to stop running and to take calcium and vitamin D supplements....

The internal flow in the rotating bucket of Pelton turbine is free water sheet flow with moving boundary. The runner operates under atmospheric and the cavitation in the bucket is still a controversial problem. While more and more field practice proved that there exists cavitation in the Pelton turbine bucket and the cavitation erosion may occur at the worst which will damage the bucket. So a w...

In this paper I use a mathematical model to simulate the effect of wind and altitude on men's and women's 4400-m race performances. Both wind speed and direction were altered to calculate the effect on the velocity profile and the final time of the sprinter. The simulation shows that for a constant wind velocity, changing the wind direction can produce a large variation in the race time and vel...

KHALED HOSSEINI has been widely acclaimed for his debut novel The Kite Runner, an international best-seller. The novel not only launched Hosseini into the limelight as an Afghan-American writer but also bridged the gap between Western literary audience and the culture of the Middle East. The novel is about the friendship of two Afghan boys through the decades, and Amir, the narrator is an expat...

Forces that are repeatedly applied to the body could lead to positive remodeling of a structure if the forces fall below the tensile limit of the structure and if sufficient time is provided between force applications. On the other hand, an overuse injury could result if there is inadequate rest time between applied forces. Running is one of the most widespread activities during which overuse i...

We analyze a model of fault-tolerant systems in a probabilistic setting. The model has been introduced under the name of “sabotage games”. A reachability problem over graphs is considered, where a “Runner” starts from a vertex u and seeks to reach some vertex in a target set F while, after each move, the adversary “Blocker” deletes one edge. Extending work by Löding and Rohde (who showed PSpace...