Abstract Sorafenib is a multikinase inhibitor used in the treatment of various solid tumors. Mucocutaneous adverse events are experienced by 70 to 90% patients receiving sorafenib, underscoring importance awareness among oncologists and dermatologists. Spiny follicular hyperkeratosis (SFH) benign rarely reported skin reaction linked sorafenib. It characterized flesh-colored or white, hyperkerat...

We present a case of an atypical diffuse cutaneous eruption due to HPV infection and Tinea in 51-year-old male patient with past medical history mild cytopenia, vasectomy difficult socio-economic situation. Differential diagnosis at initial visit included Epidermodysplasia Verruciformis vs Pityriasis Rubra Pilaris Secondary Syphilis Xanthoma Disseminatum presentation less likely other. Through ...

BACKGROUND UVA1 phototherapy has recently demonstrated high levels of efficacy and tolerability for treating a variety of inflammatory and neoplastic skin diseases. OBJECTIVE The purpose of the present study was to assess the clinical efficacy of UVA1 (340~400 nm) phototherapy for treating pityriasis rosea and to assess the course of the disease after treatment. METHODS Fifteen patients wit...

espanolLa pitiriasis rubra pilaris es una dermatosis infrecuente cuya etiologia se desconoce; caracteriza por papulas foliculares hiperqueratosicas, placas eritematosas y escamosas que pueden progresar a eritrodermia, con islas de piel sana, queratodermia palmoplantar. Los subtipos III, IV V, segun la clasificacion Griffiths, observan exclusivamente en ninos. El tratamiento esta constituye un d...

Pityriasis rosea is a common erythematosquamous eruption, typically presenting along the cleavage lines of the skin. A wide spectrum of atypical manifestations may challenge even the most experienced physician. Here we report a rare case of a suberythrodermic pityriasis rosea with gigantic plaques after an influenza vaccination, and we discuss the possible triggers of atypical manifestations of...

Pityriasis rosea (PR) is a common skin eruption in children that is characterized by a single skin patch that usually evolves into a widespread exanthem after one week. The duration of PR is typically six weeks and the condition is selflimited with excellent prognosis. The diagnosis is established by proper history taking and physical examination of the skin lesions. Laboratory investigations a...