BACKGROUND Retinopathy of prematurity(ROP) is the most common serious ophthalmic disease in preterm infants. Human milk may provide a protective effect for ROP; however, beneficial effects of human milk preclude randomized trials. Therefore, we conducted a retrospective analysis comparing early postnatal nutrition with ROP development. OBJECTIVE Evaluate relationship between early postnatal n...

Purpose. This study aims to evaluate the regression of retinopathy of prematurity (ROP) after one intravitreal injection of bevacizumab and the factors that influenced it. Methods. This retrospective case series was carried out at the "Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania. It includes all the consecutive infants treated for ROP with one intravitreal bevaciz...

Rho-type small GTP-binding plant proteins function as two-state molecular switches in cellular signalling. There is accumulating evidence that Rho-of-plants (ROP) signalling is positively controlled by plant receptor kinases, through the ROP guanine nucleotide exchange factor proteins. These signalling modules regulate cell polarity, cell shape, hormone responses, and pathogen defence, among ot...

Until recently, the treatment of potentially blinding retinopathy of prematurity (ROP) has been relatively straightforward. The 2003 publication1 of the multicenter ETROP (Early Treatment for Retinopathy of Prematurity) randomized trial indicated improved outcomes with the use of peripheral retinal ablation for eyes with type 1 ROP, defined as zone I ROP with plus disease (ie, abnormal dilation...

Objective. To report the current incidence and the need for surgery for retinopathy of prematurity (ROP) in neonates (22–36 weeks’ gestational age [GA], July 1, 1989 through June 30, 1997). Study Design. Retrospective analyses using computerized perinatal database kept on all admissions, a review of patient charts, and eye examination log books. Setting. Level 3 regional referral NICU. Patients...

Retinopathy of prematurty (ROP) is a relentless disease of the retina in premature children that in advanced cases leads to blindness. A good screening programme ensures early detection and timely intervention. Surgical results in advanced stages of ROP are very poor. Creating awareness, training of specialists end development of viable ROP centres is an urgent need. New research insights have ...

BACKGROUND With the increasing survival rates of preterm infants, the incidence of retinopathy of prematurity (ROP) is also increasing. This study aimed to investigate the risk factors for ROP in Neonatal Intensive Care Unit, and the effects of laser therapy. METHODS Thirty-five premature infants with various other diseases were studied. Data were collected including gender, gestational age, ...

PURPOSE To determine whether a multivariate risk model can select infants with low-risk eyes for an alternative protocol that reduces retinopathy of prematurity (ROP) screening without loss of effectiveness. METHODS This was a retrospective, nonrandomized, comparative study. We assigned 712 eyes of 357 premature infants of 401-1,250 g birth weights as high or low risk for prethreshold or thre...

purpose : to evaluate the efficacy of autologous plasmin in pediatric vitrectomy and to report the anatomic outcomes of autologous plasmin assisted pediatric vitrectomy methods : in an interventional prospective study, thirty-four pediatric patients with vitreoretinal disorders who needed vitrectomy during 2008 to 2010, included in the study. the patients were divided into two groups: the retin...

Intruduction: This study was conducted to determine blood levels of leptin in premature infants with proliferative ROP.Retinopathy of prematurity (ROP) is a postnatal disorder of retinal vessels that develops in the incompletely vascularized retina of preterm infants. This disorder regresses in most patients but can lead to severe visual impairment. There is evidence that leptin stimulates angi...